Viperin Antibody, clone MaP.VIP | EMD Millipore MABF106 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Viperin Antibody, clone MaP.VIP

catalog :

MABF106

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

MaP.VIP

The same clone is also sold as:

Abcam: ab107359
LifeSpan Biosciences: LS-C139851

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation, flow cytometry

citations: 4

Published Application/Species/Sample/Dilution	Reference
western blot; human; loading ...; fig 1b	Gaidt M, Ebert T, Chauhan D, Ramshorn K, Pinci F, Zuber S, et al. The DNA Inflammasome in Human Myeloid Cells Is Initiated by a STING-Cell Death Program Upstream of NLRP3. Cell. 2017;171:1110-1124.e18 pubmed publisher
western blot; mouse; 1:1000; loading ...; fig 4b	Pépin G, Nejad C, Thomas B, Ferrand J, McArthur K, Bardin P, et al. Activation of cGAS-dependent antiviral responses by DNA intercalating agents. Nucleic Acids Res. 2017;45:198-205 pubmed publisher
western blot; mouse; fig 3	Pépin G, Ferrand J, Höning K, Jayasekara W, Cain J, Behlke M, et al. Cre-dependent DNA recombination activates a STING-dependent innate immune response. Nucleic Acids Res. 2016;44:5356-64 pubmed publisher
western blot; mouse	Jakobs C, Perner S, Hornung V. AIM2 Drives Joint Inflammation in a Self-DNA Triggered Model of Chronic Polyarthritis. PLoS ONE. 2015;10:e0131702 pubmed publisher

product information

Catalog Number :

MABF106

Subcategory :

Inflammation & Immunology

Product Name :

Anti-Viperin Antibody, clone MaP.VIP

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q8WXG1

Host Name :

Mouse

Antigen :

Viperin

Clone :

MaP.VIP

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Viperin Antibody, clone MaP.VIP

Cross Reactivity :

Mouse;Human;Rat

Background :

Virus inhibitory protein endoplasmic reticulum-associated interferon-inducible (Viperin) belongs to the RSAD2 family and is highly inducible by both type I and type II interferons, but little or no induction is observed in moncytic cell lines. Studies suggest that viperin is involved in host antiviral response, as viperin induction is observed from viral infections. Research also reveals that viperin inhibits influenza replication by disrupting its release from the plasmic membrane through the altering of plasma membrane fluidity by affecting formation of lipid rafts. Lipid rafts are known detergent-resistant microdomian sites for influenza budding.

ALT Names :

Radical S-adenosyl methionine domain-containing protein 2;Cytomegalovirus-induced gene 5 protein;Viperin;Virus inhibitory protein, endoplasmic reticulum-associated, interferon-inducible

Immunogen :

Recombinant protein corresponding to human Viperin.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry;Flow Cytometry;Immunoprecipitation;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt