phospho Histone H3 (Ser10), clone 6G8B7 | EMD Millipore MABE939 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho Histone H3 (Ser10), clone 6G8B7

catalog :

MABE939

quantity :

100 μg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

6G8B7

reactivity :

human, mouse

application :

western blot, ELISA, immunocytochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; fig 4	Bian F, Gao F, Kartashov A, Jegga A, Barski A, Das S. Polycomb repressive complex 1 controls uterine decidualization. Sci Rep. 2016;6:26061 pubmed publisher

product information

Catalog Number :

MABE939

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho Histone H3 (Ser10), clone 6G8B7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84243

Host Name :

Rat

Antigen :

H3F3A

Clone :

6G8B7

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2aκ

Product Description :

Anti-phospho Histone H3 (Ser10), clone 6G8B7

Cross Reactivity :

Human

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine. Histone H3 variants (H3.1, H3.2 and H3.3) have been implicated in the epigenetic memory of cellular state. Genome-wide patterns of H3.3 are dependent on amino acid sequence and change with cellular differentiation at developmentally regulated loci.

ALT Names :

Histone H3.3, Anti-phospho Histone H3 (Ser10), clone 6G8B7

Immunogen :

KLH-conjugated linear peptide corresponding to human Histone H3 (Ser10).

Package Size :

100 μg

Uses :

Western Blotting, Immunocytochemistry, ELISA

Storage :

Stable for 1 year at 2-8°C from date of receipt