Aiolos Antibody, clone 9D10 | EMD Millipore MABE911 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Aiolos Antibody, clone 9D10

catalog :

MABE911

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9D10

reactivity :

human, mouse

application :

western blot, chromatin immunoprecipitation, ChIP-Seq

product information

Catalog Number :

MABE911

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Aiolos Antibody, clone 9D10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9UKT9

Host Name :

Mouse

Antigen :

IKZF3

Clone :

9D10

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2bκ

Product Description :

Anti-Aiolos Antibody, clone 9D10

Cross Reactivity :

Human, Mouse

Background :

Aiolos is a zinc finger DNA binding transcription factor important in lymphocyte differentiation and development. Aiolos plays an essential role in the regulation of B-cell differentiation including, proliferation and maturation to plasma cells. Aiolos also works as a cofactor in gene suppression via its interaction with the transcription factor FOXP3 in regulatory T cells as well, and Aiolos is involved in various chromatin functions too through its interaction with histone deacetylase complexes containing HDAC1, MTA2 and SIN3A. Aiolos is localized in the nucleus primarily but can be found in the cytoplasm depending upon the cellular situation. Aiolos is expressed in leukocytes and found in high concentration in spleen and thymus and has multiple isoforms. Activity is regulated via phosphorylation.

ALT Names :

Zinc finger protein Aiolos, Ikaros family zinc finger protein 3

Immunogen :

Recombinant protein corresponding to human Aiolos.

Package Size :

100 μg

Uses :

Western Blotting, ChIP-seq, Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt