Histone H3.3 Antibody, clone 4H2D7 | EMD Millipore MABE872 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Histone H3.3 Antibody, clone 4H2D7

catalog :

MABE872

quantity :

200 μg

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

4H2D7

reactivity :

human, mouse

application :

western blot, immunocytochemistry, chromatin immunoprecipitation

citations: 1

Reference
O Callaghan P, Noborn F, Sehlin D, Li J, Lannfelt L, Lindahl U, et al. Apolipoprotein E increases cell association of amyloid-? 40 through heparan sulfate and LRP1 dependent pathways. Amyloid. 2014;21:76-87 pubmed publisher

product information

Catalog Number :

MABE872

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Histone H3.3 Antibody, clone 4H2D7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84243

Host Name :

Rat

Antigen :

H3F3B

Clone :

4H2D7

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2aκ

Product Description :

Anti-Histone H3.3 Antibody, clone 4H2D7

Cross Reactivity :

Human, Mouse

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. The N-terminal tail of histone H3 protrudes from the globular nucleosome core and can undergo several different types of epigenetic modifications that influence cellular processes. These modifications include the covalent attachment of methyl or acetyl groups to lysine and arginine amino acids and the phosphorylation of serine or threonine.

ALT Names :

Histone H3.3, H3F3A, H3.3A, H3F3

Immunogen :

KLH-conjugated linear peptide corresponding to human Histone H3.3.

Package Size :

200 μg

Uses :

Western Blotting, Immunocytochemistry, Chromatin Immunoprecipitation (ChIP)

Storage :

Stable for 1 year at 2-8°C from date of receipt