MiTF Antibody, clone 3D1.2 | EMD Millipore MABE78 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

MiTF Antibody, clone 3D1.2

catalog :

MABE78

quantity :

200 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3D1.2

reactivity :

human, mouse

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABE78

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-MiTF Antibody, clone 3D1.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O75030

Host Name :

Mouse

Antigen :

MiTF

Clone :

3D1.2

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-MiTF Antibody, clone 3D1.2

Cross Reactivity :

Human;Mouse

Background :

Microphthalmia-associated transcription factor (MiTF) is a basic helix loop helix leucine zipper (b HLH ZIP) transcription factor implicated in pigmentation, and development of mast cells and bone. Mutations in MiTF cause auditory pigmentary syndromes in humans, such as Waardenburg syndrome type II and type IIa, and Tietz syndrome. There are two known isoforms of MiTF, differing by 66 amino acids at the N-terminus. Shorter forms are expressed in melanocytes and run as two bands at 52 kDa and 56 kDa, whereas the longer Mi form runs as a cluster of bands at 60-70 kDa in osteoclasts and in B16 melonoma cells (but not other melanoma cell lines), as well as mast cells and heart. MiTF plays a critical role in the differentiation of various cell types as neural crest-derived melanocytes, mast cells, osteoclasts and optic cup-derived retinal pigment epithelium.

ALT Names :

Microphthalmia-associated transcription factor;Class E basic helix-loop-helix protein 32;bHLHe32

Immunogen :

GST-tagged recombinant protein corresponding to human MiTF.

Package Size :

200 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt