EMD Millipore

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

antibody

Anti-phospho-SMC1 (Ser360), clone EPR4498(2), Rabbit Monoclonal Antibody

MABE584

100 µL

monoclonal

rabbit

nonconjugated

phosphorylated

EPR4498

western blot, immunohistochemistry

MABE584

Epigenetics & Nuclear Function

Anti-phospho-SMC1 (Ser360), clone EPR4498(2), Rabbit Monoclonal Antibody

Antibodies

Monoclonal Antibody

Q14683

Rabbit

SMC1A

EPR4498(2)

Unpurified

Unpurified

IgG

Anti-phospho-SMC1 (Ser360), clone EPR4498(2), Rabbit Monoclonal Antibody

Human

Structural maintenance of chromosomes protein 1A (SMC protein 1A or SMC-1-alpha or SMC-1A), also known as Sb1.8, and encoded by the gene names SMC1A or SMC1 or SMC1L1, is involved in chromosome cohesion during cell cycle and in DNA repair and a central component of the cohesin complex. It has been reported that SMC1 is a component of the DNA damage response network that functions as an effector in the ATM/NBS1-dependent S-phase checkpoint pathway. SMC1 associates with BRCA1 and is phosphorylated in response to IR in an ATM- and NBS1-dependent manner. SMC1 is phosphorylated in an ATM-dependent manner. Mutations in SMC1 have been assoicated with Cornelia de Lange syndrome 2.

Structural maintenance of chromosomes protein 1A, SMC protein 1A, SMC-1-alpha, SMC-1A, Sb1.8

Synthetic peptide corresponding to human phospho-SMC1 (Ser360).

100 µL

Western Blotting, Immunohistochemistry

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance. Note: Variability in freezer temperatures below -20°C may cause glycerol containing solutions to become frozen during storage.