Phosphoepitope SR proteins Antibody, clone 1H4 | EMD Millipore MABE50 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Phosphoepitope SR proteins Antibody, clone 1H4

catalog :

MABE50

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H4

reactivity :

human, mouse, fruit fly

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1,000	Fernández Nogales M, Cabrera J, Santos Galindo M, Hoozemans J, Ferrer I, Rozemuller A, et al. Huntington's disease is a four-repeat tauopathy with tau nuclear rods. Nat Med. 2014;20:881-5 pubmed publisher
western blot; mouse; 1:3000	Wang Q, Chikina M, Pincas H, Sealfon S. Homer1 alternative splicing is regulated by gonadotropin-releasing hormone and modulates gonadotropin gene expression. Mol Cell Biol. 2014;34:1747-56 pubmed publisher
	Liu P, Fu X, Zhu J. Juvenile hormone-regulated alternative splicing of the taiman gene primes the ecdysteroid response in adult mosquitoes. Proc Natl Acad Sci U S A. 2018;115:E7738-E7747 pubmed publisher

product information

Catalog Number :

MABE50

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Phosphoepitope SR proteins Antibody, clone 1H4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Phosphoepitope SR proteins

Clone :

1H4

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Phosphoepitope SR proteins Antibody, clone 1H4

Cross Reactivity :

Rat;Mouse;Human

Background :

Ser-Arg-rich (SR) proteins make up a family of functionally and structurally conserved phosphoproteins, and are required components of alternative and constitutive pre-mRNA splicing. SR proteins are characterized by their modular composition consisting of two domains of interest: an N-terminal RNA recognition motif (RRM) which serves in the determination of DNA-binding specificity, and the RS domain, an arginine and serine rich, C-terminal domain that serves as a shuttling and localization director of SR proteins and as a splicing activation domain. They are involved in various aspects of pre-mRNA splicing and in spliceosome assembly including; the identification and appropriation of splice-sites, and the manipulation of alternative splicing regulation.

ALT Names :

Ser-Arg-rich proteins

Immunogen :

Purified oocyte nuclei containing xenopus SR proteins.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt