phospho Histone H3 (Thr11) Antibody, clone N123/48 | EMD Millipore MABE435 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

phospho Histone H3 (Thr11) Antibody, clone N123/48

catalog :

MABE435

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

antigen modification :

phosphorylated

clone name :

N123/48

application :

western blot, immunocytochemistry

product information

Catalog Number :

MABE435

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-phospho Histone H3 (Thr11) Antibody, clone N123/48

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q6LED0

Host Name :

Mouse

Clone :

N123/48

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1

Product Description :

Anti-phospho Histone H3 (Thr11) Antibody, clone N123/48

Cross Reactivity :

Human

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified, and Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Di- and tri-methylation of histone H3 are gene silencing marks, while removal of these marks by the demethylase genes Jmjd1a and Jmjd2c leads to gene activation.

ALT Names :

Histone H3.1

Immunogen :

Linear peptide corresponding to rat Histone H3 phosphorylated at Thr11.

Package Size :

100 µL

Uses :

Western Blotting, Immunocytochemistry, Dot Blot

Storage :

Stable for 1 year at 2-8°C from date of receipt