| Published Application/Species/Sample/Dilution | Reference |
|---|
- western blot; human; loading ...; fig s3f
| Guillén Boixet J, Kopach A, Holehouse A, Wittmann S, Jahnel M, Schlüßler R, et al. RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation. Cell. 2020;181:346-361.e17 pubmed publisher |
- western blot; mouse; loading ...; fig 1c
| Smith H, Freeman O, Butcher A, Holmqvist S, Humoud I, Schätzl T, et al. Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration. Neuron. 2020;: pubmed publisher |
- immunocytochemistry; mouse; 1:100; loading ...; fig e5c
| Ries R, Zaccara S, Klein P, Olarerin George A, Namkoong S, Pickering B, et al. m6A enhances the phase separation potential of mRNA. Nature. 2019;571:424-428 pubmed publisher |
- western blot; human; loading ...; fig s1d
| Phung B, Ciesla M, Sanna A, Guzzi N, Beneventi G, Cao Thi Ngoc P, et al. The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma. Cell Rep. 2019;27:3573-3586.e7 pubmed publisher |
- immunocytochemistry; mouse; 1:100; loading ...; fig 7d
| López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher |
- western blot; human; fig 3j
| Lafita Navarro M, Kim M, Borenstein Auerbach N, Venkateswaran N, Hao Y, Ray R, et al. The aryl hydrocarbon receptor regulates nucleolar activity and protein synthesis in MYC-expressing cells. Genes Dev. 2018;32:1303-1308 pubmed publisher |
- immunocytochemistry; Xenopus laevis; loading ...; fig s3a
| Cagnetta R, Frese C, Shigeoka T, Krijgsveld J, Holt C. Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome. Neuron. 2018;99:29-46.e4 pubmed publisher |
- immunocytochemistry; human; loading ...; fig 4
| Lessel D, Schob C, Küry S, Reijnders M, Harel T, Eldomery M, et al. De Novo Missense Mutations in DHX30 Impair Global Translation and Cause a Neurodevelopmental Disorder. Am J Hum Genet. 2017;101:716-724 pubmed publisher |
- western blot; human; 1:1000; loading ...
| Aviner R, Hofmann S, Elman T, Shenoy A, Geiger T, Elkon R, et al. Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis. Nucleic Acids Res. 2017;45:5945-5957 pubmed publisher |
- western blot; human; loading ...; fig 6c
| Lyons S, Achorn C, Kedersha N, Anderson P, Ivanov P. YB-1 regulates tiRNA-induced Stress Granule formation but not translational repression. Nucleic Acids Res. 2016;44:6949-60 pubmed publisher |
- western blot; mouse; 1:4000; fig 7
| Ebert S, Dyle M, Bullard S, Dierdorff J, Murry D, Fox D, et al. Identification and Small Molecule Inhibition of an Activating Transcription Factor 4 (ATF4)-dependent Pathway to Age-related Skeletal Muscle Weakness and Atrophy. J Biol Chem. 2015;290:25497-511 pubmed publisher |
- western blot; human; loading ...; fig 6b
| Loveless T, Topacio B, Vashisht A, Galaang S, Ulrich K, Young B, et al. DNA Damage Regulates Translation through β-TRCP Targeting of CReP. PLoS Genet. 2015;11:e1005292 pubmed publisher |
- immunocytochemistry; mouse; 1:5000
| Lin Y, Pang X, Huang G, Jamison S, Fang J, Harding H, et al. Impaired eukaryotic translation initiation factor 2B activity specifically in oligodendrocytes reproduces the pathology of vanishing white matter disease in mice. J Neurosci. 2014;34:12182-91 pubmed publisher |
- western blot; human; 1:20000
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| Zhan Y, Yu S, Yang S, Qiu X, Meng C, Tan L, et al. Newcastle Disease virus infection activates PI3K/Akt/mTOR and p38 MAPK/Mnk1 pathways to benefit viral mRNA translation via interaction of the viral NP protein and host eIF4E. PLoS Pathog. 2020;16:e1008610 pubmed publisher |
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| Elvira R, Cha S, Noh G, Kim K, Han J. PERK-Mediated eIF2α Phosphorylation Contributes to The Protection of Dopaminergic Neurons from Chronic Heat Stress in Drosophila. Int J Mol Sci. 2020;21: pubmed publisher |
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| Klein M, Younts T, Cobo C, Buxbaum A, Aow J, Erdjument Bromage H, et al. Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons. Cell Rep. 2019;29:1789-1799.e6 pubmed publisher |
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| Pringle E, Robinson C, McCormick C. Kaposi's Sarcoma-Associated Herpesvirus Lytic Replication Interferes with mTORC1 Regulation of Autophagy and Viral Protein Synthesis. J Virol. 2019;93: pubmed publisher |
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| Fang M, Markmiller S, Vu A, Javaherian A, Dowdle W, Jolivet P, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019;: pubmed publisher |
| Smith H, Hirukawa A, Sanguin Gendreau V, Nandi I, Dufour C, Zuo D, et al. An ErbB2/c-Src axis links bioenergetics with PRC2 translation to drive epigenetic reprogramming and mammary tumorigenesis. Nat Commun. 2019;10:2901 pubmed publisher |
| Fourrière L, Kasri A, Gareil N, Bardin S, Bousquet H, Pereira D, et al. RAB6 and microtubules restrict protein secretion to focal adhesions. J Cell Biol. 2019;: pubmed publisher |
| Das R, Schwintzer L, Vinopal S, Roca E, Sylvester M, Oprişoreanu A, et al. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. J Cell Sci. 2019;: pubmed publisher |
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| Otsuka Y, Egawa K, Kanzaki N, Izumo T, Rogi T, Shibata H. Quercetin glycosides prevent dexamethasone-induced muscle atrophy in mice. Biochem Biophys Rep. 2019;18:100618 pubmed publisher |
| Koren S, Hamm M, Meier S, Weiss B, Nation G, Chishti E, et al. Tau drives translational selectivity by interacting with ribosomal proteins. Acta Neuropathol. 2019;137:571-583 pubmed publisher |
| Hodgson R, Varanda B, Ashe M, Allen K, Campbell S. Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs. Mol Biol Cell. 2019;30:942-958 pubmed publisher |
| Haghandish N, Baldwin R, Morettin A, Dawit H, Adhikary H, Masson J, et al. PRMT7 methylates eukaryotic translation initiation factor 2α and regulates its role in stress granule formation. Mol Biol Cell. 2019;30:778-793 pubmed publisher |
| Rabouw H, Langereis M, Anand A, Visser L, de Groot R, Walter P, et al. Small molecule ISRIB suppresses the integrated stress response within a defined window of activation. Proc Natl Acad Sci U S A. 2019;116:2097-2102 pubmed publisher |
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| Parzych K, Saavedra García P, Valbuena G, Al Sadah H, Robinson M, Penfold L, et al. The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation. Oncogene. 2019;38:3216-3231 pubmed publisher |
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| Hussain S, Turnbull M, Wise H, Jagger B, Beard P, Kovacikova K, et al. Mutation of Influenza A Virus PA-X Decreases Pathogenicity in Chicken Embryos and Can Increase the Yield of Reassortant Candidate Vaccine Viruses. J Virol. 2019;93: pubmed publisher |
| Lavado A, Park J, Pare J, Finkelstein D, Pan H, Xu B, et al. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Dev Cell. 2018;47:576-591.e8 pubmed publisher |
| Hartmann H, Hornburg D, Czuppa M, Bader J, Michaelsen M, Farny D, et al. Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity. Life Sci Alliance. 2018;1:e201800070 pubmed publisher |
| Abraham R, Hauer D, McPherson R, Utt A, Kirby I, Cohen M, et al. ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication. Proc Natl Acad Sci U S A. 2018;115:E10457-E10466 pubmed publisher |
| Böhm B, Fehrl Y, Janczi T, Schneider N, Burkhardt H. Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation. PLoS ONE. 2018;13:e0203847 pubmed publisher |
| Gallo S, Ricciardi S, Manfrini N, Pesce E, Oliveto S, Calamita P, et al. RACK1 Specifically Regulates Translation through Its Binding to Ribosomes. Mol Cell Biol. 2018;38: pubmed publisher |
| Tiku V, Kew C, Mehrotra P, Ganesan R, Robinson N, Antebi A. Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance. Nat Commun. 2018;9:3607 pubmed publisher |
| Crossland H, Smith K, Atherton P, Wilkinson D. The metabolic and molecular mechanisms of hyperammonaemia- and hyperethanolaemia-induced protein catabolism in skeletal muscle cells. J Cell Physiol. 2018;233:9663-9673 pubmed publisher |
| Aweida D, Rudesky I, Volodin A, Shimko E, Cohen S. GSK3-β promotes calpain-1-mediated desmin filament depolymerization and myofibril loss in atrophy. J Cell Biol. 2018;217:3698-3714 pubmed publisher |
| Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed publisher |
| Mota R, Parry T, Yates C, Qiang Z, Eaton S, Mwiza J, et al. Increasing Cardiomyocyte Atrogin-1 Reduces Aging-Associated Fibrosis and Regulates Remodeling in Vivo. Am J Pathol. 2018;188:1676-1692 pubmed publisher |
| Bütepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, et al. Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription. Sci Rep. 2018;8:6748 pubmed publisher |
| Rajgor D, Sanderson T, Amici M, Collingridge G, Hanley J. NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity. EMBO J. 2018;37: pubmed publisher |
| Norrmen C, Figlia G, Pfistner P, Pereira J, Bachofner S, Suter U. mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation. J Neurosci. 2018;38:4811-4828 pubmed publisher |
| Wang W, Chen S, Das S, Losert W, Parent C. Adenylyl cyclase A mRNA localized at the back of cells is actively translated in live chemotaxing Dictyostelium. J Cell Sci. 2018;131: pubmed publisher |
| Awasthi S, Verma M, Mahesh A, K Khan M, Govindaraju G, Rajavelu A, et al. DDX49 is an RNA helicase that affects translation by regulating mRNA export and the levels of pre-ribosomal RNA. Nucleic Acids Res. 2018;46:6304-6317 pubmed publisher |
| Cioni J, Wong H, Bressan D, Kodama L, Harris W, Holt C. Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function. Neuron. 2018;97:1078-1093.e6 pubmed publisher |
| Bussey K, Lau U, Schumann S, Gallo A, Osbelt L, Stempel M, et al. The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein. PLoS Pathog. 2018;14:e1006937 pubmed publisher |
| Chapple R, Hu T, Tseng Y, Liu L, Kitano A, Luu V, et al. ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response. elife. 2018;7: pubmed publisher |
| Yang X, Hu Z, Fan S, Zhang Q, Zhong Y, Guo D, et al. Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. PLoS Pathog. 2018;14:e1006901 pubmed publisher |
| Weng Y, Wang X, An R, Cassin J, Vissers C, Liu Y, et al. Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System. Neuron. 2018;97:313-325.e6 pubmed publisher |
| Perry B, Rahnert J, Xie Y, Zheng B, Woodworth Hobbs M, Price S. Palmitate-induced ER stress and inhibition of protein synthesis in cultured myotubes does not require Toll-like receptor 4. PLoS ONE. 2018;13:e0191313 pubmed publisher |
| Barragán Iglesias P, Lou T, Bhat V, Megat S, Burton M, Price T, et al. Inhibition of Poly(A)-binding protein with a synthetic RNA mimic reduces pain sensitization in mice. Nat Commun. 2018;9:10 pubmed publisher |
| Chauche C, Nogales A, Zhu H, Goldfarb D, Ahmad Shanizza A, Gu Q, et al. Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1. J Virol. 2018;92: pubmed publisher |
| Hu J, Sun F, Handel M. Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice. Biol Reprod. 2018;98:102-114 pubmed publisher |
| Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017;8:2005 pubmed publisher |
| Filer D, Thompson M, Takhaveev V, Dobson A, Kotronaki I, Green J, et al. RNA polymerase III limits longevity downstream of TORC1. Nature. 2017;552:263-267 pubmed publisher |
| Choi R, McConahay A, Jeong H, McClellan J, Hardee J, Carson J, et al. Tribbles 3 regulates protein turnover in mouse skeletal muscle. Biochem Biophys Res Commun. 2017;493:1236-1242 pubmed publisher |
| Li C, Götz J. Somatodendritic accumulation of Tau in Alzheimer's disease is promoted by Fyn-mediated local protein translation. EMBO J. 2017;36:3120-3138 pubmed publisher |
| Huang C, Kolokoltsova O, Mateer E, Koma T, Paessler S. Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells. J Virol. 2017;91: pubmed publisher |
| Beirowski B, Wong K, Babetto E, Milbrandt J. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. Proc Natl Acad Sci U S A. 2017;114:E4261-E4270 pubmed publisher |
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| Hörnberg H, Cioni J, Harris W, Holt C. Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1. J Neurosci. 2016;36:12697-12706 pubmed |
| Silva R, Sattlegger E, Castilho B. Perturbations in actin dynamics reconfigure protein complexes that modulate GCN2 activity and promote an eIF2 response. J Cell Sci. 2016;129:4521-4533 pubmed |
| Moretti I, Ciciliot S, Dyar K, Abraham R, Murgia M, Agatea L, et al. MRF4 negatively regulates adult skeletal muscle growth by repressing MEF2 activity. Nat Commun. 2016;7:12397 pubmed publisher |
| Hjerpe R, Bett J, Keuss M, Solovyova A, McWilliams T, Johnson C, et al. UBQLN2 Mediates Autophagy-Independent Protein Aggregate Clearance by the Proteasome. Cell. 2016;166:935-949 pubmed publisher |
| Jones C, Pashler A, Towler B, Robinson S, Newbury S. RNA-seq reveals post-transcriptional regulation of Drosophila insulin-like peptide dilp8 and the neuropeptide-like precursor Nplp2 by the exoribonuclease Pacman/XRN1. Nucleic Acids Res. 2016;44:267-80 pubmed publisher |
| Panas M, Kedersha N, McInerney G. Methods for the characterization of stress granules in virus infected cells. Methods. 2015;90:57-64 pubmed publisher |
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| Jamison S, Lin Y, Lin W. Pancreatic endoplasmic reticulum kinase activation promotes medulloblastoma cell migration and invasion through induction of vascular endothelial growth factor A. PLoS ONE. 2015;10:e0120252 pubmed publisher |
| Kim S, Martin K. Neuron-wide RNA transport combines with netrin-mediated local translation to spatially regulate the synaptic proteome. elife. 2015;4: pubmed publisher |
| David A, Yewdell J. Applying the ribopuromycylation method to detect nuclear translation. Methods Mol Biol. 2015;1228:133-42 pubmed publisher |
| Tran K, Li Y, Duan H, Arora D, Lim H, Wang W. Identification of small molecules that protect pancreatic β cells against endoplasmic reticulum stress-induced cell death. ACS Chem Biol. 2014;9:2796-806 pubmed publisher |
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| Cary G, Yoon S, Torres C, Wang K, Hays M, Ludlow C, et al. Identification and characterization of a drug-sensitive strain enables puromycin-based translational assays in Saccharomyces cerevisiae. Yeast. 2014;31:167-78 pubmed publisher |
