Puromycin Antibody, clone 4G11 | EMD Millipore MABE342 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Puromycin Antibody, clone 4G11

catalog :

MABE342

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4G11

application :

western blot, immunocytochemistry, immunoprecipitation, FACS

citations: 3

Reference
Dewe J, Fuller B, Lentini J, Kellner S, Fu D. TRMT1-Catalyzed tRNA Modifications Are Required for Redox Homeostasis To Ensure Proper Cellular Proliferation and Oxidative Stress Survival. Mol Cell Biol. 2017;37: pubmed publisher
Sullivan A, Beach E, Stetzik L, Perry A, D Addezio A, Cushing B, et al. A novel model for neuroendocrine toxicology: neurobehavioral effects of BPA exposure in a prosocial species, the prairie vole (Microtus ochrogaster). Endocrinology. 2014;155:3867-81 pubmed publisher
Papanikolaou T, Amano T, Lennington J, Sink K, Farrar A, Salamone J, et al. In-vitro analysis of Pitx3 in mesodiencephalic dopaminergic neuron maturation. Eur J Neurosci. 2009;29:2264-75 pubmed publisher

product information

Catalog Number :

MABE342

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-Puromycin Antibody, clone 4G11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Puromycin

Clone :

4G11

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Puromycin Antibody, clone 4G11

Cross Reactivity :

Human;All

Background :

Puromycin is an aminonucleoside antibiotic, derived from the Streptomyces alboniger bacterium, that functions as a protein synthesis inhibitor that blocks translation through premature chain termination in the ribosome. Monoclonal antibodies to puromycin may be used with standard immunochemical methods to directly monitor translation, a method known as surface sensing of translation (SUnSET). Part of the molecule resembles the 3' end of the aminoacylated tRNA, making it useful for protein translation analysis. Puromycin induces DNA fragmentation in thymocytes and in human HL-60 leukemia cells.

Immunogen :

Puromycin from Streptomyces alboniger

Package Size :

100 µL

Uses :

Western Blotting;Fluorescence Activated Cell Sorting (FACS);Immunofluorescence;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt