c-ErbB2/c-Neu Antibody, clone 9G6 | EMD Millipore MABE332 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

c-ErbB2/c-Neu Antibody, clone 9G6

catalog :

MABE332

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9G6

The same clone is also sold as:

BD Biosciences: 554300
Abcam: ab16899
Santa Cruz Biotechnology: sc-08
OriGene: AM33015PU-N

reactivity :

human

application :

immunohistochemistry, immunoprecipitation

product information

Catalog Number :

MABE332

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-c-ErbB2/c-Neu Antibody, clone 9G6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P04626

Host Name :

Mouse

Antigen :

c-ErbB2/c-Neu

Clone :

9G6

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-c-ErbB2/c-Neu Antibody, clone 9G6

Cross Reactivity :

Human

Background :

The ErbB2 (HER2, c-Neu, ErbB2, c-erbB2, or HER2/neu) protein is member of the human epidermal growth factor receptor (HER) family. It is a receptor tyrosine kinase containing an intracellular kinase domain and an extracellular ligand domain, although no endogenous ligand has yet been found. ErbB2 dimerizes with ErbB1, 3, and 4, and can activate different pathways including the PI3K, PLCγ, and MAPK pathways, depending on the ErbB receptor involved. Coupling with ErbB3 activates the PI3K pathway, whereas coupling with any of these three receptors can induce the MAPK pathway. ErbB2 signaling promotes cell proliferation and inhibits apoptosis. ErbB2 is overexpressed in various cancers and may play a role in the development and metastasis of gliomas, and ovarian, breast, lung, and gastric cancer.

ALT Names :

Receptor tyrosine-protein kinase erbB-2;Metastatic lymph node gene 19 protein;MLN 19;Proto-oncogene Neu;Proto-oncogene c-ErbB-2;Tyrosine kinase-type cell surface receptor HER2;p185erbB2;CD340

Immunogen :

Whole cells overexpressing human c-ErbB2/c-Neu.

Package Size :

100 μg

Uses :

Immunoprecipitation;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt