5-Hydroxymethylcytosine (5hmC) Antibody, clone HMC-MA01 | EMD Millipore MABE317 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

5-Hydroxymethylcytosine (5hmC) Antibody, clone HMC-MA01

catalog :

MABE317

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

HMC-MA01

application :

immunocytochemistry, immunoprecipitation

product information

Catalog Number :

MABE317

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-5-Hydroxymethylcytosine (5hmC) Antibody, clone HMC-MA01

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

5-Hydroxymethylcytosine (5hmC)

Clone :

HMC-MA01

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-5-Hydroxymethylcytosine (5hmC) Antibody, clone HMC-MA01

Cross Reactivity :

All

Background :

5-Hydroxymethylcytosine is a DNA pyrimidine nitrogen base formed from the enzymatic conversion of 5-methylcytosine into 5-hydroxymethylcytosine by the TET family of iron-dependent oxygenases. Data suggests that every mammalian cell contains 5-hydroxymethylcytosine, but the levels vary depending on the cell type; data also suggests that levels of 5-hydroxymethylcytosine increases with age. The highest levels are found in neuronal cells of the central nervous system and certain mammalian tissues such as mouse Purkinje and granule neurons. Although the exact function has not been fully elucidated, studies suggest that 5-hydroxymethlcytosine may regulate gene expression or initiate DNA demethylation.

ALT Names :

5hmeC;5' hydroxymethyl cytosine;5'OH methyl cytosine;5'OHmeC

Immunogen :

BSA-conjugated recombinant Hydroxymethylcytosine DNA.

Specificity :

This antibody detects 5-Hydroxymethylcytosine, but not 5-Methylcytosine or unmethylated cytosine.

Package Size :

100 µL

Uses :

Dot Blot;Immunocytochemistry;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt