unmethylated Histone H3 (Lys9) Antibody, clone 9B1-2G6, Alexa Fluor® 647 Conjugate | EMD Millipore MABE263-AF647 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

unmethylated Histone H3 (Lys9) Antibody, clone 9B1-2G6, Alexa Fluor® 647 Conjugate

catalog :

MABE263-AF647

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

AF647

clone name :

9B1-2G6

The same clone is also sold as:

BioLegend: 815701

reactivity :

human

application :

immunocytochemistry

product information

Catalog Number :

MABE263-AF647

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-unmethylated Histone H3 (Lys9) Antibody, clone 9B1-2G6, Alexa Fluor® 647 Conjugate

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P68431

Host Name :

Mouse

Antigen :

HIST1H3A

Conjugate :

AlexaFluor®647

Purification Method :

Protein G purified

Product Description :

Anti-unmethylated Histone H3 (Lys9) Antibody, clone 9B1-2G6, Alexa Fluor® 647 Conjugate

Cross Reactivity :

Human

Background :

Histone H3 is one of the five main histone proteins involved in the structure of chromatin in eukaryotic cells. Featuring a main globular domain and a long N-terminal tail, H3 is involved with the structure of the nucleosomes of the 'beads on a string' structure. Histone proteins are highly post-translationally modified however Histone H3 is the most extensively modified of the five histones. Histone H3 sequence variants and variable modification states are thought to play a role in the dynamic and long term regulation of genes. Trimethylation of histone H3 on Lys9 (H3K9me3) is one of the most highly studied epigenetic marks. H3K9me3 functions in the repression of euchromatic genes, and in epigenetic control of heterochromatin assembly, most likely by acting as a recognition motif for the binding of chromatin-associated proteins, such as Swi6 or HP1α. The enzymes responsible for H3K9 trimethylation are SUV39H1 and SUV39H2. While lysine demethylation is mediated by enzymes such as JmjC domain-containing proteins.

ALT Names :

Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/I, Histone, H3/j, Histone H3/k, Histone H3/l

Immunogen :

KLH-conjugated linear peptide corresponding to human unmethylated Histone H3 (Lys9).

Package Size :

100 µL

Uses :

Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt