SRp55 Antibody, clone 9-1-56 | EMD Millipore MABE152 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SRp55 Antibody, clone 9-1-56

catalog :

MABE152

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9-1-56

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 1a	Hernández I, Cabrera J, Santos Galindo M, Sanchez Martin M, Dominguez V, García Escudero R, et al. Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism. Brain. 2020;143:2207-2219 pubmed publisher
western blot; human; fig 1	Cabrera J, Lucas J. MAP2 Splicing is Altered in Huntington's Disease. Brain Pathol. 2017;27:181-189 pubmed publisher
immunoprecipitation; human western blot; human	Eifler T, Shao W, Bartholomeeusen K, Fujinaga K, JÃ¤ger S, Johnson J, et al. Cyclin-dependent kinase 12 increases 3' end processing of growth factor-induced c-FOS transcripts. Mol Cell Biol. 2015;35:468-78 pubmed publisher

product information

Catalog Number :

MABE152

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-SRp55 Antibody, clone 9-1-56

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q13247

Host Name :

Mouse

Antigen :

SRp55

Clone :

9-1-56

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-SRp55 Antibody, clone 9-1-56

Cross Reactivity :

Human

Background :

Pre-mRNA-splicing factor SRp55 is a member of the serine/arginine-rich (SR) protein family. This group of proteins is found mainly in the nucleus where they play a critical role in regulated and constitutive splicing of precursor mRNAs. SRp55 is involved in the constitutive process for mRNA splicing, and is able to mediate alternative splice site selection. Considered one of the more ubiquitous of the splice factors, SRp55 is upregulated in response to DNA damage when p53 is lacking. SRp55 is significantly phosphorylated on RS domain serine residues.

ALT Names :

splicing factor, arginine/serine-rich 6;arginine/serine-rich splicing factor 6;splicing factor, arginine/serine-rich, 55 kDa;Pre-mRNA-splicing factor SRP55;pre-mRNA splicing factor SRP55

Immunogen :

MBP-tagged recombinant protein corresponding to human SRp55.

Package Size :

100 μg

Uses :

Western Blotting;Immunoprecipitation;Immunocytochemistry;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt