SRp20 Antibody, clone 7B4 | EMD Millipore MABE116 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SRp20 Antibody, clone 7B4

catalog :

MABE116

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

7B4

The same clone is also sold as:

Santa Cruz Biotechnology: sc-13510

reactivity :

human, mouse

application :

western blot, immunocytochemistry

citations: 3

Published Application/Species/Sample/Dilution	Reference
western blot; human; fig 4	Majerciak V, Lu M, Li X, Zheng Z. Attenuation of the suppressive activity of cellular splicing factor SRSF3 by Kaposi sarcoma-associated herpesvirus ORF57 protein is required for RNA splicing. RNA. 2014;20:1747-58 pubmed publisher
	Ajiro M, Jia R, Wang R, Deng C, Zheng Z. Adapted Resistance to the Knockdown Effect of shRNA-Derived Srsf3 siRNAs in Mouse Littermates. Int J Biol Sci. 2015;11:1248-56 pubmed publisher
	Wong J, Garner B, Halliday G, Kwok J. Srp20 regulates TrkB pre-mRNA splicing to generate TrkB-Shc transcripts with implications for Alzheimer's disease. J Neurochem. 2012;123:159-71 pubmed publisher

product information

Catalog Number :

MABE116

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-SRp20 Antibody, clone 7B4

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P84103

Host Name :

Mouse

Antigen :

SRp20

Clone :

7B4

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-SRp20 Antibody, clone 7B4

Cross Reactivity :

Human;Mouse;Rat

Background :

Splicing factor, arginine/serine-rich 3 (SRp20) is a member of the splicing factor SR family and contains an RRP (RNA recognition motif) domain. SRp20 has been shown as being localized to nuclear sites of RNA transcription and localization of SR protein. It is involved in mediating RNA export in association with the proliferation and/or maturation of cells. SRp20 has also been implicated in recent studies as having a regulatory role in the early-to-late switch of Papillomavirus, and as being target for the regulation of splicing modifications by the β-catenin/TCF4 pathway. Up-regulation of SRp20 has also been linked with malignant epithelial ovarian cancer.

ALT Names :

splicing factor, arginine/serine-rich 3;Pre-mRNA-splicing factor SRP20;splicing factor, arginine/serine-rich, 20-kD

Immunogen :

KLH-conjugated linear peptide corresponding to human SRp20.

Package Size :

100 μg

Uses :

Western Blotting;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt