FOXA2 Antibody, clone 3C10 | EMD Millipore MABE110 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

FOXA2 Antibody, clone 3C10

catalog :

MABE110

quantity :

200 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3C10

reactivity :

human

application :

western blot

citations: 3

Reference
Yamamori S, Itakura M, Sugaya D, Katsumata O, Sakagami H, Takahashi M. Differential expression of SNAP-25 family proteins in the mouse brain. J Comp Neurol. 2011;519:916-32 pubmed publisher
Boichuk S, Hu L, Hein J, Gjoerup O. Multiple DNA damage signaling and repair pathways deregulated by simian virus 40 large T antigen. J Virol. 2010;84:8007-20 pubmed publisher
Blickwedehl J, Agarwal M, Seong C, Pandita R, Melendy T, Sung P, et al. Role for proteasome activator PA200 and postglutamyl proteasome activity in genomic stability. Proc Natl Acad Sci U S A. 2008;105:16165-70 pubmed publisher

product information

Catalog Number :

MABE110

Subcategory :

Epigenetics & Nuclear Function

Product Name :

Anti-FOXA2 Antibody, clone 3C10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9Y261

Host Name :

Mouse

Antigen :

FOXA2

Clone :

3C10

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-FOXA2 Antibody, clone 3C10

Cross Reactivity :

Human

Background :

Also known as hepatocyle nuclear factor 3-beta (HNF-3B), Forkhead box protein A2 (FOXA2) belongs to the forkhead class of DNA-binding proteins. This family of transcription factors influences gene expression in endodermally-derived tissues such as lung, liver, stomach, pancreas, and intestine. Foxa2 has also been detected in ectodermally-derived tissues such as kidney, uterus and vagina, and seminal and coagulating glands during development. Several studies show that FOXA proteins help facilitiate the binding of several nuclear receptors to their respective targets in a context-dependent manner, and are thereby implicated in various functions including cellular maintenance, differentiation, metabolism, and organogenesis. Aberrant function of FOXA proteins are attributed to diseases states such as diabetes and Parkinson's disease.

ALT Names :

Hepatocyte nuclear factor 3-beta;HNF-3-beta;HNF-3B;Forkhead box protein A2;Transcription factor 3B;TCF-3B

Immunogen :

Recombinant protein corresponding to the human FOXA2.

Package Size :

200 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt