SSEA-5 Antibody, clone 8e11 | EMD Millipore MABD88 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SSEA-5 Antibody, clone 8e11

catalog :

MABD88

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8e11

application :

immunocytochemistry, flow cytometry

citations: 6

Reference
Cuerquis J, Romieu Mourez R, Francois M, Routy J, Young Y, Zhao J, et al. Human mesenchymal stromal cells transiently increase cytokine production by activated T cells before suppressing T-cell proliferation: effect of interferon-? and tumor necrosis factor-? stimulation. Cytotherapy. 2014;16:191-202 pubmed publisher
Nigro J, White J, Ramshaw J, Haylock D, Nilsson S, Werkmeister J. The effect of bovine endosteum-derived particles on the proliferation of human mesenchymal stem cells. Biomaterials. 2010;31:5689-99 pubmed publisher
Campeau P, Rafei M, Boivin M, Sun Y, Grabowski G, Galipeau J. Characterization of Gaucher disease bone marrow mesenchymal stromal cells reveals an altered inflammatory secretome. Blood. 2009;114:3181-90 pubmed publisher
Bieback K, Hecker A, Kocaömer A, Lannert H, Schallmoser K, Strunk D, et al. Human alternatives to fetal bovine serum for the expansion of mesenchymal stromal cells from bone marrow. Stem Cells. 2009;27:2331-41 pubmed publisher
Romieu Mourez R, Francois M, Boivin M, Bouchentouf M, Spaner D, Galipeau J. Cytokine modulation of TLR expression and activation in mesenchymal stromal cells leads to a proinflammatory phenotype. J Immunol. 2009;182:7963-73 pubmed publisher
Romieu Mourez R, Francois M, Boivin M, Stagg J, Galipeau J. Regulation of MHC class II expression and antigen processing in murine and human mesenchymal stromal cells by IFN-gamma, TGF-beta, and cell density. J Immunol. 2007;179:1549-58 pubmed

product information

Catalog Number :

MABD88

Subcategory :

Stem Cell Research

Product Name :

Anti-SSEA-5 Antibody, clone 8e11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

SSEA-5

Clone :

8e11

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-SSEA-5 Antibody, clone 8e11

Cross Reactivity :

Human

Background :

Stage-specific embryonic antigen (SSEA)-5 is an H type-1 glycan that is highly and specifically expressed on human embryonic stem cells (hESCs), the human blastocyst inner cell mass and undifferentiated human pluripotent stem cells (hPSCs). Expression of SSEA-5 in hESCs and hPSCs rapidly decreases upon differentiation and is considered an indicator of undifferentiated PSCs. This SSEA-5 antibody is capable of identifying undifferentiated pluripotent stem cells in heterogeneous populations, and when used in conjunction with other pluripotency surface markers (CD9 and CD90 or CD50 and CD200), it can be used to immunodeplete residual teratoma-causing cells from incompletely differentiated embryonic stem cell cultures.

Immunogen :

Undifferentiated H9 hESCs

Package Size :

100 µL

Uses :

Flow Cytometry;Immunocytochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt