LIMD1 Antibody, clone 3F2/C6 | EMD Millipore MABD85 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

LIMD1 Antibody, clone 3F2/C6

catalog :

MABD85

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F2/C6

reactivity :

human, dogs

application :

western blot, immunohistochemistry, immunocytochemistry, immunoprecipitation

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; dogs; 1:500; fig s1a western blot; dogs; 1:1000; fig s3a immunocytochemistry; human; 1:500; loading ...; fig s1a	Ibar C, Kirichenko E, Keepers B, Enners E, Fleisch K, Irvine K. Tension-dependent regulation of mammalian Hippo signaling through LIMD1. J Cell Sci. 2018;131: pubmed publisher

product information

Catalog Number :

MABD85

Subcategory :

Stem Cell Research

Product Name :

Anti-LIMD1 Antibody, clone 3F2/C6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9UGP4

Host Name :

Mouse

Antigen :

LIMD1

Clone :

3F2/C6

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-LIMD1 Antibody, clone 3F2/C6

Cross Reactivity :

Human

Background :

LIMD1 (LIM domains-containing protein 1) is a tumor suppressor and member of the Ajuba family of LIM domain-containing proteins. LIMD1 interacts with retinoblastoma protein (pRB), inhibits E2F-mediated transcription, and suppresses the expression of the majority of genes with E2F1-responsive elements. Recently, LIMD1 has been implicated in regulating cellular processes involved in hypoxia. LIMD1 acts as a molecular scaffold, simultaneously binding the prolyl hydroxylases (PHDs) and von Hippel Lindau tumor suppressors (VHL), thereby assembling a PHD-LIMD1-VHL protein complex and creating an enzymatic niche that enables efficient degradation of HIF-1α.

ALT Names :

LIM domain-containing protein 1

Immunogen :

Recombinant protein corresponding to human LIMD1

Specificity :

This antibody recognizes human LIMD1.

Package Size :

100 µL

Uses :

Immunocytochemistry;Immunohistochemistry;Immunoprecipitation;Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt