Oct-4 Antibody, clone 9B7 | EMD Millipore MABD76 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Oct-4 Antibody, clone 9B7

catalog :

MABD76

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9B7

The same clone is also sold as:

Cell Signaling Technology: 4286
Abnova: MAB14128
Invitrogen: MA1-104, MA1-104-HRP, MA1-104-D488
Enzo Life Sciences: ADI-905-855-100

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry

citations: 4

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; mouse; 1:100	Deng S, Zhang Y, Xu C, Ma D. MicroRNA-125b-2 overexpression represses ectodermal differentiation of mouse embryonic stem cells. Int J Mol Med. 2015;36:355-62 pubmed publisher
	Hepburn A, Steele R, Veeratterapillay R, Wilson L, Kounatidou E, Barnard A, et al. The induction of core pluripotency master regulators in cancers defines poor clinical outcomes and treatment resistance. Oncogene. 2019;38:4412-4424 pubmed publisher
	Matson J, Dumitru R, Coryell P, Baxley R, Chen W, Twaroski K, et al. Rapid DNA replication origin licensing protects stem cell pluripotency. elife. 2017;6: pubmed publisher
	Suchorska W, Augustyniak E, Richter M, Trzeciak T. Comparison of Four Protocols to Generate Chondrocyte-Like Cells from Human Induced Pluripotent Stem Cells (hiPSCs). Stem Cell Rev. 2017;13:299-308 pubmed publisher

product information

Catalog Number :

MABD76

Subcategory :

Stem Cell Research

Product Name :

Anti-Oct-4 Antibody, clone 9B7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q01860

Host Name :

Mouse

Antigen :

Oct 4

Clone :

9B7

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Oct-4 Antibody, clone 9B7

Cross Reactivity :

Mouse;Human

Background :

The POU5F1 gene expresses the POU-domain transcription factor, Octamer-4 (Oct-4), which is widely regarded as a hallmark of pluripotent stem cells. The relationship of Oct-4 to pluripotent stem cells is indicated by its tightly restricted expression to undifferentiated pluripotent stem cells. Upon differentiation to somatic lineages, the expression of Oct-4 disappears rapidly. Unlike the majority of pluripotent stem cell markers, the biological role of Oct-4 has been well characterized. Studies performed in mice point to the critical role of Oct-4 in the establishment and/or maintenance of pluripotent stem cells in an uncommitted state.

ALT Names :

POU domain, class 5, transcription factor 1;Octamer-binding protein 3;Oct-3;Octamer-binding protein 4;Oct-4;Octamer-binding transcription factor 3;OTF-3

Immunogen :

Recombinant protein corresponding to human Oct-4.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry;Immunofluorescence

Storage :

Stable for 1 year at 2-8°C from date of receipt