Achaete-scute homolog 1 Antibody, clone 6D8.1 | EMD Millipore MABD64 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Achaete-scute homolog 1 Antibody, clone 6D8.1

catalog :

MABD64

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6D8.1

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; human; 1:200; loading ...; fig 5h	Li S, Zang Z, He J, Chen X, Yu S, Pei Y, et al. Expression of pannexin 1 and 2 in cortical lesions from intractable epilepsy patients with focal cortical dysplasia. Oncotarget. 2017;8:6883-6895 pubmed publisher

product information

Catalog Number :

MABD64

Subcategory :

Cell Structure

Product Name :

Anti-Achaete-scute homolog 1 Antibody, clone 6D8.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P50553

Host Name :

Mouse

Antigen :

Achaete-scute homolog 1

Clone :

6D8.1

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-Achaete-scute homolog 1 Antibody, clone 6D8.1

Cross Reactivity :

Human

Background :

Achaete-scute homolog 1 (ASCL1), also known as MASH1, ASH1 or HASH1, is a basic helix-loop-helix transcription factor. ASCL1 binds to the E box (5'-CANNTG-3') which then activates transcription. For efficient DNA binding, dimerization with other BHLH proteins is required. Achaete Scute proteins may also be involved in the determination of neuronal precursors in the central and peripheral nervous systems. It is expressed in fetal brain and is essential for the proper development and the survival of subsets of autonomic neurons. It is highly expressed in medullary thyroid cancer and small cell lung cancer.

ALT Names :

Achaete-scute homolog 1;ASH-1;Hash1;Class A basic helix-loop-helix protein 46;bHLHa46

Immunogen :

KLH-conjugated linear peptide corresponding to human Achaete-scute homolog 1.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt