DMP-1 (CT) Antibody, clone 8G10.3 | EMD Millipore MABD19 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

DMP-1 (CT) Antibody, clone 8G10.3

catalog :

MABD19

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8G10.3

reactivity :

human, mouse, rat

application :

immunohistochemistry, immunohistochemistry - paraffin section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; rat; 1:200; loading ...; fig 4c	Oya K, Ishida K, Nishida T, Sato S, Kishino M, Hirose K, et al. Immunohistochemical analysis of dentin matrix protein 1 (Dmp1) phosphorylation by Fam20C in bone: implications for the induction of biomineralization. Histochem Cell Biol. 2017;147:341-351 pubmed publisher

product information

Catalog Number :

MABD19

Subcategory :

Stem Cell Research

Product Name :

Anti-DMP-1 (CT) Antibody, clone 8G10.3

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P98193

Host Name :

Mouse

Antigen :

DMP-1 (CT)

Clone :

8G10.3

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-DMP-1 (CT) Antibody, clone 8G10.3

Cross Reactivity :

Human;Rat;Mouse

Background :

Dentin matrix protein 1, also known as DMP-1, is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in DMP-1 are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia.

ALT Names :

Dentin matrix acidic phosphoprotein 1;DMP-1;Dentin matrix protein 1;AG1

Immunogen :

57 kDa fragments isolated from rat bone

Specificity :

This antibody detects the C-Terminus of DMP-1.

Package Size :

100 μg

Uses :

Immunohistochemistry;Dot Blot

Storage :

Stable for 1 year at 2-8°C from date of receipt