BMR2 Antibody, clone 3F6 | EMD Millipore MABD171 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

BMR2 Antibody, clone 3F6

catalog :

MABD171

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F6

The same clone is also sold as:

Abnova: MAB10610
Novus Biologicals: NBP2-37624
ProMab: 30184
MilliporeSigma: SAB5300505
OriGene: AM06597SU-N
LifeSpan Biosciences: LS-B9843

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - paraffin section; mouse; fig 1	Liu J, Saito K, Maruya Y, Nakamura T, Yamada A, Fukumoto E, et al. Mutant GDF5 enhances ameloblast differentiation via accelerated BMP2-induced Smad1/5/8 phosphorylation. Sci Rep. 2016;6:23670 pubmed publisher
immunohistochemistry - paraffin section; human; 1:500 western blot; human; 1:500	Luo T, Cui S, Bian C, Yu X. Crosstalk between TGF-?/Smad3 and BMP/BMPR2 signaling pathways via miR-17-92 cluster in carotid artery restenosis. Mol Cell Biochem. 2014;389:169-76 pubmed publisher

product information

Catalog Number :

MABD171

Subcategory :

Stem Cell Research

Product Name :

Anti-BMR2 Antibody, clone 3F6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

BMR2

Clone :

3F6

Conjugate :

Ascites

Isotype :

IgG1

Product Description :

Anti-BMR2 Antibody, clone 3F6

Cross Reactivity :

Human;Mouse;Rat;Monkey

Background :

BMPR2 a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-β superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease.

ALT Names :

Bone morphogenetic protein receptor type-2BMP type-2 receptor;BMPR-2;Bone morphogenetic protein receptor type II;BMP type II receptor;BMPR-II

Immunogen :

Purified recombinant fragment of human BMR2 expressed in E. Coli.

Package Size :

100 µL

Uses :

Western Blotting;Immunofluorescence;Immunohistochemistry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.