This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Wnt-5a Antibody, clone 6F2
catalog :
MABD136
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
6F2

The same clone is also sold as:
reactivity :
human, rat
application :
western blot, immunohistochemistry, immunocytochemistry
product information
Catalog Number :
MABD136
Subcategory :
Stem Cell Research
Product Name :
Anti-Wnt-5a Antibody, clone 6F2
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Gene ID :
P41221
Host Name :
Mouse
Antigen :
Wnt-5a
Clone :
6F2
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Wnt-5a Antibody, clone 6F2
Cross Reactivity :
Human;Rat
Background :
The Wnt family of cysteine-rich proteins constitutes a group of ligands known for their roles in development such as cell differentiation, proliferation, migration and embryonic patterning. They have also been implicated in the formation of tumors. Wnts are involved in the stimulation of several signaling cascades that have been divided into two types; the canonical pathway, and the non-canonical pathway. Wnt-5a is considered to be a non-canonical ligand for the Wnt signaling pathway and is a ligand to the frizzled family of seven transmembrane receptors. When interacting with ROR2, Wnt-5a is considered to inhibit tumor formation due to Wnt-5a’s suppression of the canonical Wnt signaling pathway. Wnt-5a is involved in activating cell migration, regulating the motility of melanoma cells, decreasing the proliferation, chondrogenesis, and migration of carcinoma cells, and inhibiting the expression of type II collagen in chondrocytes. Wnt-5a is a requirement to the endothelial differentiation and vascularization of Embryonic Stem Cells, and is also necessary to the development of mammary glands, limb outgrowth, and the genital tubercle.
ALT Names :
Protein Wnt-5a
Immunogen :
Purified recombinant fragment of human Wnt-5a expressed in E. Coli.
Package Size :
100 µL
Uses :
Western Blotting;Immunofluorescence;Immunohistochemistry
Storage :
Stable for 1 year at 2-8°C from date of receipt
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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