PRDM1 Antibody, clone 5E7 | EMD Millipore MABD129 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PRDM1 Antibody, clone 5E7

catalog :

MABD129

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5E7

The same clone is also sold as:

Invitrogen: MA5-15611
LifeSpan Biosciences: LS-C109134
ProMab: 30020

reactivity :

human

application :

western blot

product information

Catalog Number :

MABD129

Subcategory :

Stem Cell Research

Product Name :

Anti-PRDM1 Antibody, clone 5E7

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O75626

Host Name :

Mouse

Antigen :

PRDM1

Clone :

5E7

Conjugate :

Ascites

Isotype :

IgG1

Product Description :

Anti-PRDM1 Antibody, clone 5E7

Cross Reactivity :

Human

Background :

PRDM1/Blimp1 is a repressor of beta-interferon gene expression. In the nucleus, PRDM1 is known to bind specifically with the Beta-interferon gene positive regulatory domain I (PRDI), and to interact with PRMT5. During B-cell differentiation, PRDM1 actively represses the transcription of the gene, c-myc, through binding its promoter and has been deemed a “master regulator” for terminal B-cell differentiation, as it is able to initiate the BCL1 cell developmental cascade. The transcription of this gene is increased upon virus infection.

ALT Names :

PR domain zinc finger protein 1;BLIMP-1;Beta-interferon gene positive regulatory domain I-binding factor;PR domain-containing protein 1;Positive regulatory domain I-binding factor 1;PRDI-BF1;PRDI-binding factor 1

Immunogen :

Purified recombinant fragment of human PRDM1 expressed in E. Coli.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.