Dux4 Antibody, clone 9A12 | EMD Millipore MABD116 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Dux4 Antibody, clone 9A12

catalog :

MABD116

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9A12

reactivity :

human, mouse

application :

western blot, immunocytochemistry, immunoprecipitation

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; 1:4000; loading ...; fig s3d western blot; human; 1:1000; loading ...; fig 2f	Full F, van Gent M, Sparrer K, Chiang C, Zurenski M, Scherer M, et al. Centrosomal protein TRIM43 restricts herpesvirus infection by regulating nuclear lamina integrity. Nat Microbiol. 2019;4:164-176 pubmed publisher
western blot; mouse; 1:1000; fig 8h	Moyle L, Blanc E, Jaka O, Prueller J, Banerji C, Tedesco F, et al. Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. elife. 2016;5: pubmed publisher

product information

Catalog Number :

MABD116

Subcategory :

Stem Cell Research

Product Name :

Anti-Dux4 Antibody, clone 9A12

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9UBX2

Host Name :

Mouse

Antigen :

Dux4

Clone :

9A12

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Dux4 Antibody, clone 9A12

Cross Reactivity :

Human

Background :

Dux4 is a homeodomain protein with a similar protein sequence to Pax3 and Pax7. Defects in Dux4 may be the cause of facioscapulohumeral muscular dystrophy (FSHD). FSHD is characterized by weakness of the muscles of the face, upper-arm and shoulder girdle. Ectopic expression of Dux4 in skeletal muscle activates the expression of stem cell and germline genes, and, when overexpressed in somatic cells, Dux4 can ultimately lead to cell death.

ALT Names :

double homeobox protein 4;Double homeobox protein 10;Double homeobox protein 4/10;Dux-4

Immunogen :

recombinant protein corresponding to the domain of: C-Terminal region of Human Dux4.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Electrophoretic Mobility Shift Assay;Immunoprecipitation

Storage :

Stable for 1 year at 2-8°C from date of receipt