Atg18 (WIPI-2) Antibody, clone 2A2 | EMD Millipore MABC91 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Atg18 (WIPI-2) Antibody, clone 2A2

catalog :

MABC91

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2A2

The same clone is also sold as:

Abcam: ab105459
OriGene: TA353546L
LifeSpan Biosciences: LS-B12856
Bio-Rad: MCA5780GA

reactivity :

human

application :

western blot, immunohistochemistry, immunocytochemistry, immunohistochemistry - paraffin section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunocytochemistry; human; loading ...; fig 7e	Park J, Jung C, Seo M, Otto N, Grunwald D, Kim K, et al. The ULK1 complex mediates MTORC1 signaling to the autophagy initiation machinery via binding and phosphorylating ATG14. Autophagy. 2016;12:547-64 pubmed publisher
	Valverde D, Yu S, Boggavarapu V, Kumar N, Lees J, Walz T, et al. ATG2 transports lipids to promote autophagosome biogenesis. J Cell Biol. 2019;218:1787-1798 pubmed publisher

product information

Catalog Number :

MABC91

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Atg18 (WIPI-2) Antibody, clone 2A2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9Y4P8

Host Name :

Mouse

Antigen :

Atg18 (WIPI-2)

Clone :

2A2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Atg18 (WIPI-2) Antibody, clone 2A2

Cross Reactivity :

Human

Background :

Atg18, also known as WIPI-2, is involved in autophagy by regulating the assembly of mulitprotein complexes by presenting a 7-bladed propeller structure for interactions with phospholipids. Atg18 is a mammalian effector of PtdIns3P and is ubiquitously expressed in a variety of cell lines. Studies show that Atg18 is recruited to early autophagosomal structural formation along with Atg16 and ULK1, and Atg18 is required for the formation of LC3-positive autophagosomes.

ALT Names :

WD repeat domain phosphoinositide-interacting protein 2;WIPI-2;WIPI49-like protein 2

Immunogen :

Linear peptide corresponding to the C-terminus of human Atg18.

Specificity :

This antibody recognizes Atg18 at the C-terminus.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt