SCARB1 Antibody, clone 5B8.2 | EMD Millipore MABC730 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SCARB1 Antibody, clone 5B8.2

catalog :

MABC730

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B8.2

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC730

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-SCARB1 Antibody, clone 5B8.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q8WTV0

Host Name :

Mouse

Antigen :

SCARB1

Clone :

5B8.2

Conjugate :

Purified

Purification Method :

Purified by ion-exchange chromatography

Isotype :

IgMκ

Product Description :

Anti-SCARB1 Antibody, clone 5B8.2

Cross Reactivity :

Human

Background :

Scavenger receptor class B member 1 (SCARB1), or CD36L1, is the membrane bound cell surface receptor for high density lipoprotein (HDL) as well as a number of related compounds such as phospholipids, cholesterol ester, and phosphatidylserine and apoptotic cells (via their expression of phosphatidylserine on their extracellular surfaces). SCARB1 is also the receptor for Hepatitis C virus glycoprotein E2 and it facilitates the attachment and entry of HCV. SCARB1 plays a critical role in cholesterol homeostasis and mediates cholesterol transfer to and from the HDL protein carriers, a process known as reverse cholesterol transport. It is highly expressed in tissues that require free cholesterol such as the liver and steroidogenic tissues (adrenals, testis, ovary). SCARB1 expression has also been associated with particular cancers including chronic myeloid leukemia (CML), breast cancer, bladder carcinoma, and prostate cancer.

ALT Names :

Scavenger receptor class B member 1, SRB1, CD36 and LIMPII analogous 1, CLA-1, CD36 antigen-like 1, Collagen type I receptor, thrombospondin receptor-like 1, SR-BI, CD36

Immunogen :

KLH-conjugated linear peptide corresponding to the extracellular domain of human SCARB1.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt