SOD1 Antibody, clone 6F5 | EMD Millipore MABC684 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SOD1 Antibody, clone 6F5

catalog :

MABC684

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6F5

The same clone is also sold as:

MyBioSource: MBS850323
Novus Biologicals: NBP1-47443
ProMab: 20349
Abnova: MAB10394
OriGene: AM06340SU-N
Invitrogen: MA5-15520
LifeSpan Biosciences: LS-C108729

reactivity :

human, mouse

application :

western blot, immunocytochemistry, flow cytometry

product information

Catalog Number :

MABC684

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-SOD1 Antibody, clone 6F5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P00441

Host Name :

Mouse

Antigen :

SOD1

Clone :

6F5

Conjugate :

Ascites

Isotype :

IgG1

Product Description :

Anti-SOD1 Antibody, clone 6F5

Cross Reactivity :

Human;Mouse

Background :

Superoxide dismutase 1 (SOD1) also known as Superoxide dismutase [Cu-Zn] to distinguish it from SOD2 which uses manganese as its cofactor, is the cytosolic form of the enzyme that catalyzes the breakdown of superoxide into oxygen and hydrogen peroxide and is our primary anti-oxidant combating enzyme. SOD1 performs its function with the help of co-factors and one protein in particular is vital to its proper functioning. Copper chaperone protein (CCS) is a metalloprotein that specifically delivers Cu to SOD1 and may activate SOD1 through direct insertion of the Cu cofactor. Interestingly, defects in SOD1 are the cause of a form of ALS (Amyotrophic Lateral Sclerosis or Lou Gehrig's disease) and much research is centered on understanding how over-active or under-active SOD1 contributes to the disease. EMD-Millipore's Anti-SOD1 mouse monoclonal antibody has been tested in western blot on HeLa, NIH3T3, A549 and A431 cell lysates and fluorescent immunocytochemistry on PANC1, SKBR-3 and 3T3-L1 cells in culture. The antibody has also been tested in flow cytometry on A431 cells in culture.

ALT Names :

ALS;SOD;ALS1;IPOA;homodimerSuperoxide dismutase [Cu-Zn];Superoxide dismutase 1;hSod1

Immunogen :

Purified recombinant fragment of human SOD1 expressed in E. Coli.

Package Size :

100 µL

Uses :

Western Blotting;Immunocytochemistry;Flow Cytometry

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.