LPL Antibody, clone 2C5 | EMD Millipore MABC674 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

LPL Antibody, clone 2C5

catalog :

MABC674

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2C5

The same clone is also sold as:

ProMab: 20331
MyBioSource: MBS850874
OriGene: AM06325SU-N
Invitrogen: MA5-15503
LifeSpan Biosciences: LS-C109104
Abnova: MAB10791

reactivity :

human

application :

western blot

product information

Catalog Number :

MABC674

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-LPL Antibody, clone 2C5

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P06858

Host Name :

Mouse

Antigen :

LPL

Clone :

2C5

Conjugate :

Ascites

Isotype :

IgG1

Product Description :

Anti-LPL Antibody, clone 2C5

Cross Reactivity :

Human

Background :

Lipoprotein lipase (LPL) is encoded by the LPL/LIPD gene in humans and is a lipase that localizes to the plasma membrane of the microvilli of hepatocytes and the luminal surface of endothelial cells in capillaries. It is expressed in a wide variety of tissues from fat and heart to muscle and mammary glands. It can also be found in the blood bound to lipoproteins. Its function is to hydrolyze triglycerides from the blood and other sources into free fatty acids; LPL also acts as receptor and binding factor for lipoprotein uptake and allows for the catalysis of VLDL from the blood. Expression and regulation of LPL differ by tissue type, some factors such as insulin can stimulate LPL expression in fat tissues, where as insulin down regulates LPL expression on muscle. Recently because serum triglyceride levels are linked with the development of cancer, LPL has become a target for cancer prevention and therapy because LPL catalyzes plasma triglycerides leading to lower levels, it is thought that LPL assisted therapy could be useful in preventing or treating cancers. EMD-Millipore’s Anti-LPL mouse monoclonal antibody has been tested on western blots using HeLa cell lysates.

ALT Names :

Lipoprotein lipase;HDLCQ11

Immunogen :

Purified recombinant fragment of human LPL expressed in E. Coli.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.