LAMP-2, clone 4G2.1 | EMD Millipore MABC59 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

LAMP-2, clone 4G2.1

catalog :

MABC59

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

4G2.1

reactivity :

human

application :

western blot

product information

Catalog Number :

MABC59

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-LAMP-2, clone 4G2.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P13473

Host Name :

Mouse

Antigen :

LAMP2

Clone :

4G2.1

Conjugate :

Purified

Purification Method :

Purified by ion-exchange chromatography

Isotype :

IgM

Product Description :

Anti-LAMP-2, clone 4G2.1

Cross Reactivity :

Human

Background :

Lysosome-associated membrane protein 2 (LAMP-2) is a highly glycosolated protein belonging to the lysosome-associated membrane protein family. This group pf proteins composes a significant portion of the lysosomal membrane and are considered crucial mediators for cellular adhesion by interacting with carbohydrate receptors. LAMP-2 is a profuse and critical component of the lysosomal membrane as it has been implicated in playing a role in lysosomal biogenesis. It also appears to be involved in later stages of phagocytosis and autophagy, where it may act to protect the lysosomal membrane from being digested, assist in signal transduction, moderate levels of acidity within the lysosomal environment, and participate in adhesion. Mutations in LAMP-2 expression have been associated with lysosomal storage diseases or LSDs, along with Danon disease, an X-linked disorder characterized by skeletal myopathy, mental retardation, and hypertrophic cardiomyopathy.

ALT Names :

Lysosome-associated membrane glycoprotein 2, LAMP-2, Lysosome-associated membrane protein 2, CD107 antigen-like family member B, CD107b

Immunogen :

KLH-conjugated linear peptide corresponding to the Topological domain (lumenal) of human LAMP-2.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt