SFRP2 Antibody, clone 80.8.6, azide free | EMD Millipore MABC539 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SFRP2 Antibody, clone 80.8.6, azide free

catalog :

MABC539

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

80.8.6

reactivity :

human

application :

immunohistochemistry

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; fig 2c	Sun Y, Zhu D, Chen F, Qian M, Wei H, Chen W, et al. SFRP2 augments WNT16B signaling to promote therapeutic resistance in the damaged tumor microenvironment. Oncogene. 2016;35:4321-34 pubmed publisher
	Kaur A, Webster M, Marchbank K, Behera R, Ndoye A, Kugel C, et al. sFRP2 in the aged microenvironment drives melanoma metastasis and therapy resistance. Nature. 2016;532:250-4 pubmed publisher

product information

Catalog Number :

MABC539

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-SFRP2 Antibody, clone 80.8.6, azide free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q96HF1

Host Name :

Mouse

Antigen :

SFRP2

Clone :

80.8.6

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2aκ

Product Description :

Anti-SFRP2 Antibody, clone 80.8.6, azide free

Cross Reactivity :

Human

Background :

Secreted frizzled-related proteins (SFRPs) may play a critical role in carcinogenesis by inhibiting the Wnt/beta-catenin signaling pathway. Secreted frizzled-related protein 2 (SFRP2) may be useful to further investigate mammary tumorigenesis as its expression increases with tumor progression in canine mammary gland tumors. SFRP2 in mouse embryos has been found to cause severe shortening of the thoracic region. Studies have shown that this protein is the essential stem cell paracrine factor that is thought to regulate myocardial survival and repair damage in the aftermath of an ischemic injury.

ALT Names :

Secreted frizzled-related protein 2, FRP-2, sFRP-2, Secreted apoptosis-related protein 1, SARP-1

Immunogen :

Linear peptide corresponding to the NTR domain of human SFRP2.

Package Size :

100 μg

Uses :

Immunohistochemistry, Inhibition

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.