Pleiotrophin Antibody, clone 3B10 | EMD Millipore MABC42 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Pleiotrophin Antibody, clone 3B10

catalog :

MABC42

quantity :

50 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3B10

reactivity :

human, chicken

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC42

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Pleiotrophin Antibody, clone 3B10

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P32760

Host Name :

Mouse

Antigen :

Pleiotrophin

Clone :

3B10

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Pleiotrophin Antibody, clone 3B10

Cross Reactivity :

Human

Background :

Pleiotrophin (PTN) also called Neurite Growth-promoting Factor 1 (NEGF1) or HARP (Heparin affin regulatory peptide) is a new member of the heparin-binding neurotrophic factor family. PTN plays an important role in development processess and promotion of neurite extension. During embryonic development, pleiotrophin is expressed in the central and peripheral nervous system, lung, kidney, gut and bone. Pleiotrophin is also expressed by several tumor cells and is thought to be involved in tumor angiogenesis. PTN initiates an angiogenic switch in different cancer models and acts as an angiogenic factor. PTN does this through an interaction with endothelial cells to initiate proliferation, migration, and tube formation.

ALT Names :

pleiotrophin;neurite growth-promoting factor 1;Heparin-binding brain mitogen;heparin binding growth factor 8;Heparin-binding growth-associated molecule;heparin affin regulatory protein;Heparin-binding neurite outgrowth-promoting factor 1;pleiotrophin (heparin binding growth factor 8, neurite growth-promoting factor 1);Osteoblast-specific factor 1;Heparin-binding growth factor 8

Immunogen :

Recombinant protein corresponding to chicken Pleiotrophin.

Package Size :

50 μg

Uses :

Immunohistochemistry;Western Blotting

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.