PDL-1/CD274 Antibody, clone 3F2.1 | EMD Millipore MABC290 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

PDL-1/CD274 Antibody, clone 3F2.1

catalog :

MABC290

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3F2.1

reactivity :

human

application :

western blot, immunohistochemistry

citations: 1

Reference
Pai S, Faquin W. Programmed cell death ligand 1 as a biomarker in head and neck cancer. Cancer Cytopathol. 2017;125:529-533 pubmed publisher

product information

Catalog Number :

MABC290

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-PDL-1/CD274 Antibody, clone 3F2.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9NZQ7

Host Name :

Mouse

Antigen :

CD274

Clone :

3F2.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-PDL-1/CD274 Antibody, clone 3F2.1

Cross Reactivity :

Human

Background :

Programmed cell death 1 ligand 1 (PDL-1) is a B7 related protein belonging to the BTN/MOG family. PDL-1 is essential for T-cell proliferation and production of IL10 and IFNG. PDL-1 reduces the secretion of IL-2 and IL-10 from memory T cells by inhibiting cell-mediated immune responses. PDL-1 may be involved in reducing allogenic CD4+ memory T-cell responses to endothelial cells. PDL-1 is highly expressed in heart, skeletal muscle, placenta, and lung and weakly expressed in thymus, spleen, kidney, and liver.

ALT Names :

Programmed cell death 1 ligand 1, PD-L1, PDCD1 ligand 1, Programmed death ligand 1, B7 homolog 1, B7-H1, CD274, PDL-1

Immunogen :

GST-tagged recombinant protein corresponding to the extracellular domain of human PDL-1/CD274.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt