RIP3 Antibody, clone 6E6.2 | EMD Millipore MABC28 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

RIP3 Antibody, clone 6E6.2

catalog :

MABC28

quantity :

200 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6E6.2

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC28

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-RIP3 Antibody, clone 6E6.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9Y572

Host Name :

Mouse

Antigen :

RIP3

Clone :

6E6.2

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-RIP3 Antibody, clone 6E6.2

Cross Reactivity :

Human;Rat

Background :

Receptor-interacting protein 3 (RIP3) contains a N-terminal kinase domain and interacts with RIP. The binding of RIP to RIP3 causes the RIP3/RIP complex to be shuttled into the tumor necrosis factor receptor-1 signaling cascade. RIP3 is known to be a very effective apoptosis inducer. Two novel splice variants of RIP3 have been discovered, RIP3 beta and RIP3 gamma, that have shown to decrease apoptosis related to full length RIP3. RIP3 gamma has been shown to be significantly up-regulated in colon and lung cancers and may play a role in tumorigenesis.

ALT Names :

Receptor-interacting serine/threonine-protein kinase 3;RIP-like protein kinase 3;Receptor-interacting protein 3;RIP-3

Immunogen :

GST-tagged recombinant protein corresponding to human RIP3 at the N-terminus.

Specificity :

This antibody recognizes RIP3 at the N-terminus.

Package Size :

200 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt