BAG3 Antibody, clone AC-2 | EMD Millipore MABC276 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

BAG3 Antibody, clone AC-2

catalog :

MABC276

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

AC-2

reactivity :

human

application :

western blot

citations: 1

Published Application/Species/Sample/Dilution	Reference
western blot; human; 1:1000; loading ...; fig 5c	Li N, Chen M, Cao Y, Li H, Zhao J, Zhai Z, et al. Bcl-2-associated athanogene 3(BAG3) is associated with tumor cell proliferation, migration, invasion and chemoresistance in colorectal cancer. BMC Cancer. 2018;18:793 pubmed publisher

product information

Catalog Number :

MABC276

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-BAG3 Antibody, clone AC-2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O95817

Host Name :

Mouse

Antigen :

BAG3

Clone :

AC-2

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-BAG3 Antibody, clone AC-2

Cross Reactivity :

Human

Background :

Bcl2-associated athanogene 3 (BAG3), also known as CAIR-1 or Bis, belongs to a family of six evolutionarily conserved co-chaperone proteins that contain a characteristic C-terminal BAG domain. In most cell types, BAG3 is localized to the cytoplasm, where it regulates the heat shock protein 70 chaperone. BAG3 is activated in response to stressful stimuli, and plays a critical role in modulating multiple cellular processes, including apoptosis, autophagy, embryonic development, and actin rearrangement. Abnormal expression of BAG3 results cardiomyopathy dilated type 1HH.

ALT Names :

BAG family molecular chaperone regulator 3;Bcl-2-associated athanogene 3;Bcl-2-binding protein Bis;Docking protein CAIR-1

Immunogen :

MAP peptide corresponding to human BAG3.

Package Size :

100 µL

Uses :

Western Blotting

Storage :

Stable for 1 year at 2-8°C from date of receipt