Caspase 10 Antibody, clone 16C5.1 | EMD Millipore MABC192 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Caspase 10 Antibody, clone 16C5.1

catalog :

MABC192

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

16C5.1

reactivity :

human, mouse

application :

western blot, immunohistochemistry, immunohistochemistry - frozen section

citations: 1

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; mouse; 1:100; loading ...; fig 2b	Panigrahi S, Manterola M, Wolgemuth D. Meiotic failure in cyclin A1-deficient mouse spermatocytes triggers apoptosis through intrinsic and extrinsic signaling pathways and 14-3-3 proteins. PLoS ONE. 2017;12:e0173926 pubmed publisher

product information

Catalog Number :

MABC192

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Caspase 10 Antibody, clone 16C5.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q92851

Host Name :

Mouse

Antigen :

Caspase 10

Clone :

16C5.1

Conjugate :

Purified

Isotype :

IgG2bκ

Product Description :

Anti-Caspase 10 Antibody, clone 16C5.1

Cross Reactivity :

Human;Rat;Mouse

Background :

Caspase-10 is a member of the peptidase C14A family and is involved in the activation cascade of caspases responsible for apoptosis execution. Caspase-10 has two death effector domains (DEDs) that bind to the DED in the adapter molecule FADD and recruits both TNFR1 and CD95 to form complexes with these receptors. Caspase-10 is expressed in many tissues and cell lines with the lowest expression found in brain, kidney, prostate, testis, and colon. Mutations in Caspase-10 have been associated with autoimmune lymphoproliferative syndrome type 2A and gastric cancer.

ALT Names :

Caspase-10;CASP-10;Apoptotic protease Mch-4;FAS-associated death domain protein interleukin-1B-converting enzyme 2;FLICE2;ICE-like apoptotic protease 4;Caspase-10 subunit p23/17;Caspase-10 subunit p12

Immunogen :

GST-tagged recombinant protein corresponding to the caspase 10 subunit p23/17 of human Caspase 10.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt