SDF-1 Antibody, clone K15C, Azide free | EMD Millipore MABC184 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

SDF-1 Antibody, clone K15C, Azide free

catalog :

MABC184

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

K15C

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, neutralization, immunohistochemistry - frozen section

citations: 2

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry - frozen section; human; fig 4	Nobutani K, Shimono Y, Mizutani K, Ueda Y, Suzuki T, Kitayama M, et al. Downregulation of CXCR4 in Metastasized Breast Cancer Cells and Implication in Their Dormancy. PLoS ONE. 2015;10:e0130032 pubmed publisher
	Pionnier N, Brotin E, Karadjian G, Hemon P, Gaudin Nomé F, Vallarino Lhermitte N, et al. Neutropenic Mice Provide Insight into the Role of Skin-Infiltrating Neutrophils in the Host Protective Immunity against Filarial Infective Larvae. PLoS Negl Trop Dis. 2016;10:e0004605 pubmed publisher

product information

Catalog Number :

MABC184

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-SDF-1 Antibody, clone K15C, Azide free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P48061

Host Name :

Mouse

Antigen :

SDF-1

Clone :

K15C

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-SDF-1 Antibody, clone K15C, Azide free

Cross Reactivity :

Human;Mouse

Background :

Stromal cell-derived factor 1 (SDF-1) is also known as C-X-C motif chemokine 12 (CXCL12), Intercrine reduced in hepatomas (IRH), and Pre-B cell growth-stimulating factor (PBSF). SDF-1 is a chemoattractant active on T-lymphocytes, monocytes, but not neutrophils. SDF-1 stimulates migration of monocytes and T-lymphocytes through its receptors, CXCR4 and CXCR7, and decreases monocyte adherence to surfaces coated with ICAM-1. SDF-1 plays a protective role after myocardial infarction, has critical functions during embryonic development and is required for B-cell lymphopoiesis, myelopoiesis in bone marrow and heart ventricular septum formation. Isoform Alpha and isoform Beta are ubiquitously expressed, with highest levels detected in liver, pancreas and spleen. Isoform Gamma is mainly expressed in heart. Isoform Delta, isoform Epsilon and isoform Theta have highest expression levels in pancreas.

ALT Names :

Stromal cell-derived factor 1;SDF-1;hSDF-1;C-X-C motif chemokine 12;Intercrine reduced in hepatomas;IRH;hIRH;Pre-B cell growth-stimulating factor;PBSF

Immunogen :

BSA-conjugated linear peptide corresponding to human SDF-1.

Specificity :

This antibody recognizes the N-terminus of SDF-1. This antibody should detected SDF-1alpha and SDF-1beta.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry;Neutralizing;ELISA

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.