Smac/Diablo Antibody, clone 3A9.1 | EMD Millipore MABC174 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Smac/Diablo Antibody, clone 3A9.1

catalog :

MABC174

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3A9.1

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC174

Subcategory :

Cell Structure

Product Name :

Anti-Smac/Diablo Antibody, clone 3A9.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q9NR28

Host Name :

Mouse

Antigen :

Smac/Diablo

Clone :

3A9.1

Conjugate :

Purified

Isotype :

IgG1κ

Product Description :

Anti-Smac/Diablo Antibody, clone 3A9.1

Cross Reactivity :

Human

Background :

Smac/DIABLO (Second Mitochondria-derived Activator of Caspases/Direct IAP Binding Protein with Low PI) is localized to the mitochondria and involved in activating programmed cell death, or apoptosis. In response to apoptotic stimuli, Smac/DIABLO is released from the mitochondria and binds anti-apoptotic IAP proteins, supressing their inhibitory activity and promoting caspase activation. This interaction involves primarily the amino-terminal residues of Smac/DIABLO with the BIR3 region of the IAP protein.

ALT Names :

Diablo homolog, mitochondrial;Direct IAP-binding protein with low pl;Second mitochondria-derived activator of caspase, Smac

Immunogen :

GST-tagged recombinant protein corresponding to human Smac/Diablo.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt