Rab27B, clone 6C10.1 | EMD Millipore MABC173 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rab27B, clone 6C10.1

catalog :

MABC173

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6C10.1

reactivity :

human

application :

western blot, immunohistochemistry, immunohistochemistry - paraffin section

product information

Catalog Number :

MABC173

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Rab27B, clone 6C10.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

O00194

Host Name :

Mouse

Antigen :

RAB27B

Clone :

6C10.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-Rab27B, clone 6C10.1

Cross Reactivity :

Human

Background :

RAB27B, also known as C25KG, is a member of the Rab GTPase superfamily. RAB27B acts as a lipid anchoring protein that is prenylated and works in vesicular fusion and protein trafficking within cells. The protein is most highly expressed in testis but can be expressed in other cell types as well. Because Rab27B is widely expressed in various tissues together with Rab27A and RAB27B has been found to have the ability to bind all of the Rab27A effectors that have been tested, Rab27A and Rab27B were initially thought to function redundantly by sharing common Rab27 effectors. However, recent evidence has indicated that by interacting with different Rab27 effectors Rab27A and Rab27B play different roles in special types of secretion (e.g. exosome secretion and mast cell secretion) even within the same cell type. Rab27B is particularly important for regulating protein secretion by pancreatic acinar cells, for instance.

ALT Names :

Ras-related protein Rab-27B, C25KG

Immunogen :

GST-tagged recombinant protein corresponding to human Rab27B.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry (Paraffin)

Storage :

Stable for 1 year at 2-8°C from date of receipt