TRAIL/CD253 Antibody, clone 6D12.2 | EMD Millipore MABC147 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

TRAIL/CD253 Antibody, clone 6D12.2

catalog :

MABC147

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

6D12.2

reactivity :

human

application :

immunohistochemistry, flow cytometry

product information

Catalog Number :

MABC147

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-TRAIL/CD253 Antibody, clone 6D12.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P50591

Host Name :

Mouse

Antigen :

TNFSF10

Clone :

6D12.2

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-TRAIL/CD253 Antibody, clone 6D12.2

Cross Reactivity :

Human

Background :

Apoptosis, or programmed cell death, occurs during normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by certain cytokines including TNF and Fas ligand of the TNF family through their death domain containing receptors, TNFR1 and Fas. A novel member in the TNF family was recently identified and designated TRAIL (for TNF-related apoptosis-inducing ligand) and Apo-2L (for Apo-2 ligand). TRAIL is a type II membrane protein and is expressed in a variety of human tissues. Two novel death domain containing receptors DR4 and DR5 have been identified as the receptor for TRAIL. Like TNF and Fas ligand, TRAIL induces apoptosis and NF-kB activation in many tissues and cells.

ALT Names :

Tumor necrosis factor ligand superfamily member 10, Apo-2 ligand, Apo-2L, TNF-related apoptosis-inducing ligand, Protein TRAIL, CD253

Immunogen :

GST-tagged recombinant protein corresponding to human TRAIL/CD253.

Package Size :

100 μg

Uses :

Flow Cytometry, Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt