Rab7A, clone 5G8.1 | EMD Millipore MABC119 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Rab7A, clone 5G8.1

catalog :

MABC119

quantity :

100 µL

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5G8.1

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC119

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Rab7A, clone 5G8.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P51149

Host Name :

Mouse

Antigen :

RAB7A

Clone :

5G8.1

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG2bκ

Product Description :

Anti-Rab7A, clone 5G8.1

Cross Reactivity :

Human

Background :

Ras-related protein Rab-7A (Rab7A, RAB7) is a small intracellular protein typically associated with cytoplasmic vesicles, phagosomes, and endosomes and is expressed in most cells but particularly high in muscle. It plays an important role in regulating the endo-lysosomal trafficking of proteins as well as in the endosomal trapping of pathogens and viruses. Besides endosome-lysosome trafficking, Rab7A functions in a variety of other critical cellular processes including nutrient uptake, growth factor mediated growth, neurotrophin transport, lipid transport, lysosome and phagosome maturation and development, as well as pathogen and virus innate immunity functions. RAB7A interacts with a number of other proteins within the cell, some important in endosome trafficking like RILP (Rab-interacting lysosomal protein) and CHM (Rab escort protein 1) others like RAC1 have a more pleiotropic impact and are part of many cellular processes, including the cell cycle, cell-cell adhesion, cytoskeletal motility, and cellular differentiation.

ALT Names :

Ras-related protein Rab-7a

Immunogen :

GST-tagged recombinant protein corresponding to human Rab7A.

Package Size :

100 µL

Uses :

Western Blotting, Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt