Podoplanin Antibody, clone NZ1.2 | EMD Millipore MABC117 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Podoplanin Antibody, clone NZ1.2

catalog :

MABC117

quantity :

100 µL

clonality :

monoclonal

host :

rat

conjugate :

nonconjugated

clone name :

NZ1.2

The same clone is also sold as:

LifeSpan Biosciences: LS-C148842, LS-C148835
MilliporeSigma: P0085
Invitrogen: MA5-16267
Novus Biologicals: NBP2-03954, NBP2-03952

reactivity :

human

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC117

Subcategory :

Apoptosis & Cancer

Product Name :

Anti-Podoplanin Antibody, clone NZ1.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q86YL7

Host Name :

Rat

Antigen :

Podoplanin

Clone :

NZ1.2

Conjugate :

Purified

Isotype :

IgG2aκ

Product Description :

Anti-Podoplanin Antibody, clone NZ1.2

Cross Reactivity :

Human

Background :

Human podoplanin (T1alpha-2, aggrus and gp36) is a 38 kDa type-1 transmembrane glycoprotein that consists of 162 amino acids, nine of which form the intracellular domain. The highly O-glycosylated extracellular domain contains a sialic acid that is linked to an alpha-2,3 galactose, which forms the main part of the protein’s carbohydrate moieties. It is expressed in a select variety of human tissues and organs, and is also found in lymphatic, but not blood vessel endothelium. While its mode of action remains unclear, podoplanin is suggested to play a critical role in several physiological processes and conditions such as cell migration, cytoskeleton organization, tissue development, and tissue repair, as well as in carcinogenesis and tumor cell invasion.

ALT Names :

Aggrus;Glycoprotein 36;Gp36;PA2.26 antigen;T1-alpha;T1A

Immunogen :

Protein sequence corresponding to the PLAG domain of human Podoplanin.

Specificity :

This antibody detects Podoplanin at the PLAG domain.

Package Size :

100 µL

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt