STK3/MST2 Antibody, clone 9G7.1 | EMD Millipore MABC111 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

STK3/MST2 Antibody, clone 9G7.1

catalog :

MABC111

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

9G7.1

reactivity :

human, rat

application :

western blot, immunohistochemistry

product information

Catalog Number :

MABC111

Subcategory :

Cell Signaling

Product Name :

Anti-STK3/MST2 Antibody, clone 9G7.1

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

Q13188

Host Name :

Mouse

Antigen :

STK3/MST2

Clone :

9G7.1

Conjugate :

Purified

Isotype :

IgMκ

Product Description :

Anti-STK3/MST2 Antibody, clone 9G7.1

Cross Reactivity :

Human;Rat

Background :

Mammalian Ste20-like kinase 2 (MST2) is a serine/threonine kinase found in the kidney, placenta, heart, lung, and brain. It regulates organ size, cell proliferation, tumorigenesis, and apoptosis. Under conditions of cell stress, such as oxidative damage, MST2 is cleaved by caspase-3, and is irreversibly autophosphorylated at Thr180. Activated MST2 forms a stable complex with STK3 and triggers a signaling cascade which inhibits the translocation of YAP1 to the nucleus and consequent suppression of YAP1-mediated apoptosis.

ALT Names :

Serine/threonine-protein kinase 3;Mammalian STE20-like protein kinase 2;MST-2;STE20-like kinase MST2;Serine/threonine-protein kinase Krs-1

Immunogen :

GST-tagged recombinant protein corresponding to human STK3/MST2.

Package Size :

100 μg

Uses :

Western Blotting;Immunohistochemistry

Storage :

Stable for 1 year at 2-8°C from date of receipt