Fibronectin (Cell Attachment Fragment) Antibody, clone 3E3, Ascites & Azide Free | EMD Millipore MAB88916-C product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Fibronectin (Cell Attachment Fragment) Antibody, clone 3E3, Ascites & Azide Free

catalog :

MAB88916-C

quantity :

100 μg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

3E3

The same clone is also sold as:

LifeSpan Biosciences: LS-C152955

reactivity :

human

application :

western blot, ELISA, immunohistochemistry, immunocytochemistry, enzyme immunoassay

product information

Catalog Number :

MAB88916-C

Subcategory :

Cell Signaling

Product Name :

Anti-Fibronectin (Cell Attachment Fragment) Antibody, clone 3E3, Ascites & Azide Free

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Gene ID :

P02751

Host Name :

Mouse

Antigen :

FN1

Clone :

3E3

Conjugate :

Purified

Purification Method :

Protein G purified

Isotype :

IgG1κ

Product Description :

Anti-Fibronectin (Cell Attachment Fragment) Antibody, clone 3E3, Ascites & Azide Free

Cross Reactivity :

Human

Background :

Fibronectin (FN), or in earlier literature also known as Cold-insoluble globulin (CIG), and is encoded by the gene named FN1/FN is an extracellular matrix protein. Fibronectins bind cell surfaces and various compounds including collagen, fibrin, heparin, DNA, and actin. Fibronectins are involved in cell adhesion, cell motility, opsonization, wound healing, and maintenance of cell shape. Fibronectin also plays an important role in bone development and bone structure formation. Additionally, when fibronectin binds the protein anastellin it forms a multiprotein complex termed superfibronectin that has been shown to inhibit tumor growth, angiogenesis and metastasis. Fibronectin protein can be found extracellularly as well as intracellularly. There are multiple isoforms produced by alternative splicing. Plasma fibronectin (a soluble dimeric form) is secreted by hepatocytes into the blood. Cellular fibronectin (dimeric or cross-linked multimeric forms), are made by fibroblasts, epithelial and other cell types, and is deposited as fibrils in the extracellular matrix.

ALT Names :

Fibronectin, FN, CIG, Cold-insoluble globulin

Immunogen :

Purified human Fibronectin, which contains the Cell Attachment Fragment, from amnion liquid.

Package Size :

100 μg

Uses :

Western Blotting, Immunohistochemistry, Enzyme Immunoassay (ELISA), Immunocytochemistry, Inhibition

Storage :

Stable for 1 year at -20°C from date of receipt. Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.