This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Cytomegalovirus Antibody, pp65, clone 12D10
catalog :
MAB8770
quantity :
100 µL
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
12D10
application :
immunocytochemistry
citations: 41
Reference
Briese M, Saal Bauernschubert L, Lüningschrör P, Moradi M, Dombert B, Surrey V, et al. Loss of Tdp-43 disrupts the axonal transcriptome of motoneurons accompanied by impaired axonal translation and mitochondria function. Acta Neuropathol Commun. 2020;8:116 pubmed publisher
Sun Y, Eshov A, Zhou J, Isiktas A, Guo J. C9orf72 arginine-rich dipeptide repeats inhibit UPF1-mediated RNA decay via translational repression. Nat Commun. 2020;11:3354 pubmed publisher
Zhan Y, Yu S, Yang S, Qiu X, Meng C, Tan L, et al. Newcastle Disease virus infection activates PI3K/Akt/mTOR and p38 MAPK/Mnk1 pathways to benefit viral mRNA translation via interaction of the viral NP protein and host eIF4E. PLoS Pathog. 2020;16:e1008610 pubmed publisher
Sarcinelli C, Dragic H, Piecyk M, Barbet V, Duret C, Barthelaix A, et al. ATF4-Dependent NRF2 Transcriptional Regulation Promotes Antioxidant Protection during Endoplasmic Reticulum Stress. Cancers (Basel). 2020;12: pubmed publisher
Chan K, Robert F, Oertlin C, Kapeller Libermann D, Avizonis D, Gutierrez J, et al. eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma. Nat Commun. 2019;10:5151 pubmed publisher
Klein M, Younts T, Cobo C, Buxbaum A, Aow J, Erdjument Bromage H, et al. Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons. Cell Rep. 2019;29:1789-1799.e6 pubmed publisher
Su Z, Kuscu C, MALIK A, Shibata E, Dutta A. Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3-mediated gene silencing. J Biol Chem. 2019;294:16930-16941 pubmed publisher
Singh A, Manjunath L, Kundu P, Sahoo S, Das A, Suma H, et al. Let-7a-regulated translational readthrough of mammalian AGO1 generates a microRNA pathway inhibitor. EMBO J. 2019;38:e100727 pubmed publisher
Fang M, Markmiller S, Vu A, Javaherian A, Dowdle W, Jolivet P, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019;: pubmed publisher
Fourrière L, Kasri A, Gareil N, Bardin S, Bousquet H, Pereira D, et al. RAB6 and microtubules restrict protein secretion to focal adhesions. J Cell Biol. 2019;: pubmed publisher
Das R, Schwintzer L, Vinopal S, Roca E, Sylvester M, Oprişoreanu A, et al. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. J Cell Sci. 2019;: pubmed publisher
Otsuka Y, Egawa K, Kanzaki N, Izumo T, Rogi T, Shibata H. Quercetin glycosides prevent dexamethasone-induced muscle atrophy in mice. Biochem Biophys Rep. 2019;18:100618 pubmed publisher
Hodgson R, Varanda B, Ashe M, Allen K, Campbell S. Cellular eIF2B subunit localization: implications for the integrated stress response and its control by small molecule drugs. Mol Biol Cell. 2019;30:942-958 pubmed publisher
Beckelman B, Yang W, Kasica N, Zimmermann H, Zhou X, Keene C, et al. Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice. J Clin Invest. 2019;129:820-833 pubmed publisher
Parzych K, Saavedra García P, Valbuena G, Al Sadah H, Robinson M, Penfold L, et al. The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation. Oncogene. 2019;38:3216-3231 pubmed publisher
Lavado A, Park J, Pare J, Finkelstein D, Pan H, Xu B, et al. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Dev Cell. 2018;47:576-591.e8 pubmed publisher
Hartmann H, Hornburg D, Czuppa M, Bader J, Michaelsen M, Farny D, et al. Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity. Life Sci Alliance. 2018;1:e201800070 pubmed publisher
López Erauskin J, Tadokoro T, Baughn M, Myers B, McAlonis Downes M, Chillon Marinas C, et al. ALS/FTD-Linked Mutation in FUS Suppresses Intra-axonal Protein Synthesis and Drives Disease Without Nuclear Loss-of-Function of FUS. Neuron. 2018;100:816-830.e7 pubmed publisher
Abraham R, Hauer D, McPherson R, Utt A, Kirby I, Cohen M, et al. ADP-ribosyl-binding and hydrolase activities of the alphavirus nsP3 macrodomain are critical for initiation of virus replication. Proc Natl Acad Sci U S A. 2018;115:E10457-E10466 pubmed publisher
Böhm B, Fehrl Y, Janczi T, Schneider N, Burkhardt H. Cell adhesion-induced transient interaction of ADAM15 with poly(A) binding protein at the cell membrane colocalizes with mRNA translation. PLoS ONE. 2018;13:e0203847 pubmed publisher
Gallo S, Ricciardi S, Manfrini N, Pesce E, Oliveto S, Calamita P, et al. RACK1 Specifically Regulates Translation through Its Binding to Ribosomes. Mol Cell Biol. 2018;38: pubmed publisher
Tiku V, Kew C, Mehrotra P, Ganesan R, Robinson N, Antebi A. Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance. Nat Commun. 2018;9:3607 pubmed publisher
Crossland H, Smith K, Atherton P, Wilkinson D. The metabolic and molecular mechanisms of hyperammonaemia- and hyperethanolaemia-induced protein catabolism in skeletal muscle cells. J Cell Physiol. 2018;233:9663-9673 pubmed publisher
Abel A, Tiwari A, Gerbec Z, Siebert J, Yang C, Schloemer N, et al. IQ Domain-Containing GTPase-Activating Protein 1 Regulates Cytoskeletal Reorganization and Facilitates NKG2D-Mediated Mechanistic Target of Rapamycin Complex 1 Activation and Cytokine Gene Translation in Natural Killer Cells. Front Immunol. 2018;9:1168 pubmed publisher
Bütepage M, Preisinger C, von Kriegsheim A, Scheufen A, Lausberg E, Li J, et al. Nucleolar-nucleoplasmic shuttling of TARG1 and its control by DNA damage-induced poly-ADP-ribosylation and by nucleolar transcription. Sci Rep. 2018;8:6748 pubmed publisher
Rajgor D, Sanderson T, Amici M, Collingridge G, Hanley J. NMDAR-dependent Argonaute 2 phosphorylation regulates miRNA activity and dendritic spine plasticity. EMBO J. 2018;37: pubmed publisher
Bussey K, Lau U, Schumann S, Gallo A, Osbelt L, Stempel M, et al. The interferon-stimulated gene product oligoadenylate synthetase-like protein enhances replication of Kaposi's sarcoma-associated herpesvirus (KSHV) and interacts with the KSHV ORF20 protein. PLoS Pathog. 2018;14:e1006937 pubmed publisher
Chapple R, Hu T, Tseng Y, Liu L, Kitano A, Luu V, et al. ERα promotes murine hematopoietic regeneration through the Ire1α-mediated unfolded protein response. elife. 2018;7: pubmed publisher
Yang X, Hu Z, Fan S, Zhang Q, Zhong Y, Guo D, et al. Picornavirus 2A protease regulates stress granule formation to facilitate viral translation. PLoS Pathog. 2018;14:e1006901 pubmed publisher
Perry B, Rahnert J, Xie Y, Zheng B, Woodworth Hobbs M, Price S. Palmitate-induced ER stress and inhibition of protein synthesis in cultured myotubes does not require Toll-like receptor 4. PLoS ONE. 2018;13:e0191313 pubmed publisher
Chauche C, Nogales A, Zhu H, Goldfarb D, Ahmad Shanizza A, Gu Q, et al. Mammalian Adaptation of an Avian Influenza A Virus Involves Stepwise Changes in NS1. J Virol. 2018;92: pubmed publisher
Green K, Glineburg M, Kearse M, Flores B, Linsalata A, Fedak S, et al. RAN translation at C9orf72-associated repeat expansions is selectively enhanced by the integrated stress response. Nat Commun. 2017;8:2005 pubmed publisher
Filer D, Thompson M, Takhaveev V, Dobson A, Kotronaki I, Green J, et al. RNA polymerase III limits longevity downstream of TORC1. Nature. 2017;552:263-267 pubmed publisher
Huang C, Kolokoltsova O, Mateer E, Koma T, Paessler S. Highly Pathogenic New World Arenavirus Infection Activates the Pattern Recognition Receptor Protein Kinase R without Attenuating Virus Replication in Human Cells. J Virol. 2017;91: pubmed publisher
Beirowski B, Wong K, Babetto E, Milbrandt J. mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells. Proc Natl Acad Sci U S A. 2017;114:E4261-E4270 pubmed publisher
Aviner R, Hofmann S, Elman T, Shenoy A, Geiger T, Elkon R, et al. Proteomic analysis of polyribosomes identifies splicing factors as potential regulators of translation during mitosis. Nucleic Acids Res. 2017;45:5945-5957 pubmed publisher
Dalet A, Argüello R, Combes A, Spinelli L, Jaeger S, Fallet M, et al. Protein synthesis inhibition and GADD34 control IFN-β heterogeneous expression in response to dsRNA. EMBO J. 2017;36:761-782 pubmed publisher
David A, Yewdell J. Applying the ribopuromycylation method to detect nuclear translation. Methods Mol Biol. 2015;1228:133-42 pubmed publisher
Di Prisco G, Huang W, Buffington S, Hsu C, Bonnen P, Placzek A, et al. Translational control of mGluR-dependent long-term depression and object-place learning by eIF2?. Nat Neurosci. 2014;17:1073-82 pubmed publisher
Copeland A, Altamura L, Van Deusen N, Schmaljohn C. Nuclear relocalization of polyadenylate binding protein during rift valley fever virus infection involves expression of the NSs gene. J Virol. 2013;87:11659-69 pubmed publisher
Adler B, Scrivano L, Ruzcics Z, Rupp B, Sinzger C, Koszinowski U. Role of human cytomegalovirus UL131A in cell type-specific virus entry and release. J Gen Virol. 2006;87:2451-60 pubmed
product information
Catalog Number :
MAB8770
Subcategory :
Infectious Diseases
Product Name :
Anti-Cytomegalovirus Antibody, pp65, clone 12D10
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
Cytomegalovirus
Clone :
12D10
Conjugate :
Ascites
Isotype :
IgG1
Product Description :
Anti-Cytomegalovirus Antibody, pp65, clone 12D10
Cross Reactivity :
Human
ALT Names :
CMV; pp65
Specificity :
Reacts with lower matrix protein pp65 of human CMV.
Package Size :
100 µL
Uses :
Immunofluorescence
Storage :
Maintain at -20°C in undiluted aliquots for up to 12 months from date of receipt. Avoid repeat freeze-thaw cycles.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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