This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
EMD Millipore
other brands :
Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava
product type :
antibody
product name :
Dengue Virus Complex Antibody, clone D3-2H2-9-21
catalog :
MAB8705
quantity :
100 μg
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
D3-2H2-9-21
reactivity :
Dengue virus, human
application :
immunocytochemistry, immunoprecipitation
citations: 23
Published Application/Species/Sample/DilutionReference
  • immunocytochemistry; human; loading ...; fig 1
Liu P, Ridilla M, Patel P, Betts L, Gallichotte E, Shahidi L, et al. Beyond attachment: Roles of DC-SIGN in dengue virus infection. Traffic. 2017;18:218-231 pubmed publisher
  • immunocytochemistry; Dengue virus; loading ...; fig 7d
Shu Q, Lennemann N, Sarkar S, Sadovsky Y, Coyne C. ADAP2 Is an Interferon Stimulated Gene That Restricts RNA Virus Entry. PLoS Pathog. 2015;11:e1005150 pubmed publisher
Baidaliuk A, Miot E, Lequime S, Moltini Conclois I, Delaigue F, Dabo S, et al. Cell-Fusing Agent Virus Reduces Arbovirus Dissemination in Aedes aegypti Mosquitoes In Vivo. J Virol. 2019;93: pubmed publisher
Jitobaom K, Tongluan N, Smith D. Involvement of voltage-dependent anion channel (VDAC) in dengue infection. Sci Rep. 2016;6:35753 pubmed publisher
Fontaine A, Jiolle D, Moltini Conclois I, Lequime S, Lambrechts L. Excretion of dengue virus RNA by Aedes aegypti allows non-destructive monitoring of viral dissemination in individual mosquitoes. Sci Rep. 2016;6:24885 pubmed publisher
Jitoboam K, Phaonakrop N, Libsittikul S, Thepparit C, Roytrakul S, Smith D. Actin Interacts with Dengue Virus 2 and 4 Envelope Proteins. PLoS ONE. 2016;11:e0151951 pubmed publisher
Medin C, Valois S, Patkar C, Rothman A. A plasmid-based reporter system for live cell imaging of dengue virus infected cells. J Virol Methods. 2015;211:55-62 pubmed publisher
Higa L, Curi B, Aguiar R, Cardoso C, De Lorenzi A, Sena S, et al. Modulation of α-enolase post-translational modifications by dengue virus: increased secretion of the basic isoforms in infected hepatic cells. PLoS ONE. 2014;9:e88314 pubmed publisher
de Alwis R, de Silva A. Measuring antibody neutralization of dengue virus (DENV) using a flow cytometry-based technique. Methods Mol Biol. 2014;1138:27-39 pubmed publisher
Thepparit C, Khakpoor A, Khongwichit S, Wikan N, Fongsaran C, Chingsuwanrote P, et al. Dengue 2 infection of HepG2 liver cells results in endoplasmic reticulum stress and induction of multiple pathways of cell death. BMC Res Notes. 2013;6:372 pubmed publisher
Ribeiro C, Lopes V, Brasil P, Coelho J, Muniz A, Nogueira R. Perinatal transmission of dengue: a report of 7 cases. J Pediatr. 2013;163:1514-6 pubmed publisher
Carrington L, Armijos M, Lambrechts L, Scott T. Fluctuations at a low mean temperature accelerate dengue virus transmission by Aedes aegypti. PLoS Negl Trop Dis. 2013;7:e2190 pubmed publisher
Carrington L, Seifert S, Armijos M, Lambrechts L, Scott T. Reduction of Aedes aegypti vector competence for dengue virus under large temperature fluctuations. Am J Trop Med Hyg. 2013;88:689-97 pubmed publisher
Vega Almeida T, Salas Benito M, De Nova Ocampo M, del Angel R, Salas Benito J. Surface proteins of C6/36 cells involved in dengue virus 4 binding and entry. Arch Virol. 2013;158:1189-207 pubmed publisher
Juárez Martínez A, Vega Almeida T, Salas Benito M, García Espitia M, De Nova Ocampo M, del Angel R, et al. Detection and sequencing of defective viral genomes in C6/36 cells persistently infected with dengue virus 2. Arch Virol. 2013;158:583-99 pubmed publisher
Barr K, Messenger A, Anderson B, Friary J, Heil G, Reece K, et al. Recovery of live virus after storage at ambient temperature using ViveST™. J Clin Virol. 2013;56:57-61 pubmed publisher
Mustafa B, Hani A, Chem Y, Mariam M, Khairul A, Abdul Rasid K, et al. Epidemiological and clinical features of dengue versus other acute febrile illnesses amongst patients seen at government polyclinics. Med J Malaysia. 2010;65:291-6 pubmed
Chua K, Mustafa B, Abdul Wahab A, Chem Y, Khairul A, Kumarasamy V, et al. A comparative evaluation of dengue diagnostic tests based on single-acute serum samples for laboratory confirmation of acute dengue. Malays J Pathol. 2011;33:13-20 pubmed
Kaptein S, De Burghgraeve T, Froeyen M, Pastorino B, Alen M, Mondotte J, et al. A derivate of the antibiotic doxorubicin is a selective inhibitor of dengue and yellow fever virus replication in vitro. Antimicrob Agents Chemother. 2010;54:5269-80 pubmed publisher
Salgado D, Eltit J, Mansfield K, Panqueba C, Castro D, Vega M, et al. Heart and skeletal muscle are targets of dengue virus infection. Pediatr Infect Dis J. 2010;29:238-42 pubmed publisher
Lambrechts L, Chevillon C, Albright R, Thaisomboonsuk B, Richardson J, Jarman R, et al. Genetic specificity and potential for local adaptation between dengue viruses and mosquito vectors. BMC Evol Biol. 2009;9:160 pubmed publisher
Goncalvez A, Engle R, St Claire M, Purcell R, LAI C. Monoclonal antibody-mediated enhancement of dengue virus infection in vitro and in vivo and strategies for prevention. Proc Natl Acad Sci U S A. 2007;104:9422-7 pubmed publisher
de Macedo F, Nicol A, Cooper L, Yearsley M, Pires A, Nuovo G. Histologic, viral, and molecular correlates of dengue fever infection of the liver using highly sensitive immunohistochemistry. Diagn Mol Pathol. 2006;15:223-8 pubmed
product information
Catalog Number :
MAB8705
Subcategory :
Infectious Diseases
Product Name :
Anti-Dengue Virus Complex Antibody, clone D3-2H2-9-21
Product Type :
Antibodies
Clonality :
Monoclonal Antibody
Host Name :
Mouse
Antigen :
Dengue Virus Complex
Clone :
D3-2H2-9-21
Conjugate :
Purified
Isotype :
IgG2a
Product Description :
Anti-Dengue Virus Complex Antibody, clone D3-2H2-9-21
Cross Reactivity :
Human
Background :
Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.
Immunogen :
Dengue type 4 virus antigens.
Specificity :
Reacts with all members of the Dengue complex.
Package Size :
100 μg
Uses :
Immunocytochemistry;Immunofluorescence
Storage :
Maintain for 6 months at 2–8°C from date of shipment. Aliquot to avoid repeated freezing and thawing. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
company information
EMD Millipore
290 Concord Road
Billerica, Massachusetts 01821
bioscienceshelp@emdchemical.com
https://www.emdmillipore.com
888-854-3417
headquarters: United States
EMD Millipore is the Life Science division of Merck KGaA of Darmstadt, Germany

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