Dengue Virus Type IV Antibody, clone 1H10-6 | EMD Millipore MAB8704 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Dengue Virus Type IV Antibody, clone 1H10-6

catalog :

MAB8704

quantity :

100 µl

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1H10-6

application :

immunocytochemistry

citations: 2

Reference
Khanam S, Pilankatta R, Khanna N, Swaminathan S. An adenovirus type 5 (AdV5) vector encoding an envelope domain III-based tetravalent antigen elicits immune responses against all four dengue viruses in the presence of prior AdV5 immunity. Vaccine. 2009;27:6011-21 pubmed publisher
Khanam S, Etemad B, Khanna N, Swaminathan S. Induction of neutralizing antibodies specific to dengue virus serotypes 2 and 4 by a bivalent antigen composed of linked envelope domains III of these two serotypes. Am J Trop Med Hyg. 2006;74:266-77 pubmed

product information

Catalog Number :

MAB8704

Subcategory :

Infectious Diseases

Product Name :

Anti-Dengue Virus Type IV Antibody, clone 1H10-6

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Dengue Virus Type IV

Clone :

1H10-6

Conjugate :

Ascites

Isotype :

IgG1

Product Description :

Anti-Dengue Virus Type IV Antibody, clone 1H10-6

Cross Reactivity :

Human

Background :

Dengue fever is an acute, mosquito-transmitted viral disease characterized by fever, headache, arthralgia (severe retro-orbital pain), myalgia, rash, nausea, and vomiting. Infections are caused by any of the four closely related, but antigenically distinct virus serotypes (DEN-1, DEN-2, DEN-3, and DEN-4). Infection with one of these serotypes does not provide cross-protective immunity, so persons living in a dengue-endemic area can have four dengue infections during their lifetimes. Dengue is primarily an urban disease of the tropics, and the viruses that cause it are maintained in a cycle that involves humans and Aedes aegypti, a domestic, day-biting mosquito that prefers to feed on humans. Although most dengue infections result in relatively mild illness, some can produce Dengue Hemorrhagic Fever (DHF) or dengue shock syndrome, with children being particularly at risk. Although epidemic outbreaks have been reported since 1779, the incidence has been increasing, with global, multiple serotype pandemics intensifying within the last 15 years. There is no specific antiviral therapy for dengue, but for both classical dengue and dengue hemorrhagic fever, symptomatic and supportive measures are effective. Important risk factors for DHF include the strain and serotype of the virus involved, as well as the age, immune status, and genetic predisposition of the patient.

Immunogen :

Dengue type 4 virus antigens (H241).

Specificity :

Reacts with the Dengue type 4 virus.

Package Size :

100 µl

Uses :

Immunofluorescence;Hemagglutination Inhibition

Storage :

Maintain at -20°C for up to 12 months from date of receipt and avoid freeze/thaw cycles.