EBV EA-R-p17 Antibody, clone 5B11 | EMD Millipore MAB8188 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

EBV EA-R-p17 Antibody, clone 5B11

catalog :

MAB8188

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

5B11

application :

western blot, ELISA, immunocytochemistry, immunoprecipitation

citations: 7

Reference
Shi M, Gan Y, Davis T, Scott R. Downregulation of the polyamine regulator spermidine/spermine N(1)-acetyltransferase by Epstein-Barr virus in a Burkitt's lymphoma cell line. Virus Res. 2013;177:11-21 pubmed publisher
Sakamoto S, Fujikawa Y, Esaka M. Analysis of ascorbic acid biosynthesis using a simple transient gene expression system in tomato fruit protoplasts. Biosci Biotechnol Biochem. 2013;77:673-5 pubmed
Kelly G, Stylianou J, Rasaiyaah J, Wei W, Thomas W, Croom Carter D, et al. Different patterns of Epstein-Barr virus latency in endemic Burkitt lymphoma (BL) lead to distinct variants within the BL-associated gene expression signature. J Virol. 2013;87:2882-94 pubmed publisher
Hatzios S, Ringgaard S, Davis B, Waldor M. Studies of dynamic protein-protein interactions in bacteria using Renilla luciferase complementation are undermined by nonspecific enzyme inhibition. PLoS ONE. 2012;7:e43175 pubmed publisher
Eskelin K, Hafrén A, Rantalainen K, Mäkinen K. Potyviral VPg enhances viral RNA Translation and inhibits reporter mRNA translation in planta. J Virol. 2011;85:9210-21 pubmed publisher
Watanabe A, Maruo S, Ito T, Ito M, Katsumura K, Takada K. Epstein-Barr virus-encoded Bcl-2 homologue functions as a survival factor in Wp-restricted Burkitt lymphoma cell line P3HR-1. J Virol. 2010;84:2893-901 pubmed publisher
Kelly G, Long H, Stylianou J, Thomas W, Leese A, Bell A, et al. An Epstein-Barr virus anti-apoptotic protein constitutively expressed in transformed cells and implicated in burkitt lymphomagenesis: the Wp/BHRF1 link. PLoS Pathog. 2009;5:e1000341 pubmed publisher

product information

Catalog Number :

MAB8188

Subcategory :

Infectious Diseases

Product Name :

Anti-EBV EA-R-p17 Antibody, clone 5B11

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

EBV EA-R-p17

Clone :

5B11

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-EBV EA-R-p17 Antibody, clone 5B11

Cross Reactivity :

Human

Background :

The Early Restricted protein (Ea-R) of Epstein-Bar Virus is encoded by the viral BHFR1 gene. Ea-R is a 17 kDa protein (p17) with protein kinase activity. Ea-R-p17 is a functional homologue of the anti-apoptotic oncoprotein bcl-2, which is expressed during the switch from latency to lytic replication and may be involved in proliferation of EBV infected cells. However, Ea-R-p17 does not appear to be essential for virus replication or transformation of B cells in vitro.

ALT Names :

Early Antigen Protein R; Nuclear Antigen; BHRF1

Specificity :

Recognizes the 17 kDa Early Restricted Protein (Ea-R-p17) of Epstein-Barr Virus by immunoblot, immunoprecipitation and immunofluorescence.

Package Size :

100 µg

Uses :

ELISA;Immunofluorescence;Immunoprecipitation;Western Blotting

Storage :

Maintain at 2-8°C in undiluted aliquots for up to 12 months from date of receipt.