Cytomegalovirus Antibody, late Antigen, clone 1G5.2 | EMD Millipore MAB8127 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cytomegalovirus Antibody, late Antigen, clone 1G5.2

catalog :

MAB8127

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

1G5.2

reactivity :

human, Human cytomegalovirus

application :

immunohistochemistry, immunocytochemistry, flow cytometry, immunohistochemistry - paraffin section, immunohistochemistry - frozen section

citations: 8

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; Human cytomegalovirus; 1:400; fig 2	Libard S, Popova S, Amini R, KÃ¤rjÃ¤ V, PietilÃ¤inen T, HÃ¤mÃ¤lÃ¤inen K, et al. Human cytomegalovirus tegument protein pp65 is detected in all intra- and extra-axial brain tumours independent of the tumour type or grade. PLoS ONE. 2014;9:e108861 pubmed publisher
immunohistochemistry - frozen section; human; 1:35 immunohistochemistry - paraffin section; human; 1:35	Cobbs C, Matlaf L, Harkins L. Methods for the detection of cytomegalovirus in glioblastoma cells and tissues. Methods Mol Biol. 2014;1119:165-96 pubmed publisher
immunohistochemistry - frozen section; human; 1:500	Yaiw K, Ovchinnikova O, Taher C, Mohammad A, Davoudi B, Shlyakhto E, et al. High prevalence of human cytomegalovirus in carotid atherosclerotic plaques obtained from Russian patients undergoing carotid endarterectomy. Herpesviridae. 2013;4:3 pubmed publisher
	Vasaikar S, Tsipras G, Landazuri N, Costa H, Wilhelmi V, Scicluna P, et al. Overexpression of endothelin B receptor in glioblastoma: a prognostic marker and therapeutic target?. BMC Cancer. 2018;18:154 pubmed publisher
	Costa H, Xu X, Overbeek G, Vasaikar S, Patro C, Kostopoulou O, et al. Human cytomegalovirus may promote tumour progression by upregulating arginase-2. Oncotarget. 2016;7:47221-47231 pubmed publisher
	Pereira L, Petitt M, Fong A, Tsuge M, Tabata T, Fang Hoover J, et al. Intrauterine growth restriction caused by underlying congenital cytomegalovirus infection. J Infect Dis. 2014;209:1573-84 pubmed publisher
	Baryawno N, Rahbar A, Wolmer Solberg N, Taher C, Odeberg J, Darabi A, et al. Detection of human cytomegalovirus in medulloblastomas reveals a potential therapeutic target. J Clin Invest. 2011;121:4043-55 pubmed publisher
	Millard A, Haberli L, Sinzger C, Ghielmetti M, Schneider M, Bossart W, et al. Efficiency of porcine endothelial cell infection with human cytomegalovirus depends on both virus tropism and endothelial cell vascular origin. Xenotransplantation. 2010;17:274-87 pubmed publisher

product information

Catalog Number :

MAB8127

Subcategory :

Infectious Diseases

Product Name :

Anti-Cytomegalovirus Antibody, late Antigen, clone 1G5.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Cytomegalovirus

Clone :

1G5.2

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Cytomegalovirus Antibody, late Antigen, clone 1G5.2

Cross Reactivity :

Human

ALT Names :

CMV

Immunogen :

Sucrose gradient purified CMV AD169 (ATCC).

Specificity :

Reacts with a late protein. Can detect CMV infection 24 hours post-infection exhibiting a cytoplasmic staining which reaches peak intensity at 72 hours. With CMV the antigens expressed at different times are listed as: Immediate Early (alpha gene expression): those antigens expressed at 3-12 hrs post-infection generally involved in Transcription such as 72kD major phosphoprotein and a few other other antigens at 60 - 80kD. Early Antigen (beta genes) a.k.a. Delayed Early or Intermediate Early: expressed at 12-24hrs post-infection. Generally enzymes and one virion structural gene preceding viral DNA synthesis. Late Antigen (gamma genes): expressed at 36-48hrs post-infection. Generally structural proteins. Major protein = 55kD

Package Size :

100 µg

Uses :

Flow Cytometry;Immunofluorescence;Immunohistochemistry (Paraffin)

Storage :

Maintain at +4°C for up to 12 months