Cytomegalovirus Antibody, blend, clone 8B1.2, 1G5.2, and 2D4.2 | EMD Millipore MAB8121 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

EMD Millipore

other brands :

Oncogene Research Products, Calbiochem, Novagen, Merck, Upstate Biotechnology, Chemicon, LINCO, Novabiochem, Guava

product type :

antibody

product name :

Cytomegalovirus Antibody, blend, clone 8B1.2, 1G5.2, and 2D4.2

catalog :

MAB8121

quantity :

100 µg

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

8B1.2, 1G5.2, and 2D4.2

reactivity :

human

application :

immunohistochemistry, immunocytochemistry, flow cytometry

citations: 3

Published Application/Species/Sample/Dilution	Reference
immunohistochemistry; human; 1:500	Zani A, Quaglia A, HadziÄ‡ N, Zuckerman M, Davenport M. Cytomegalovirus-associated biliary atresia: An aetiological and prognostic subgroup. J Pediatr Surg. 2015;50:1739-45 pubmed publisher
flow cytometry; human immunocytochemistry; human	Eifler M, Uecker R, Weisbach H, Bogdanow B, Richter E, KÃ¶nig L, et al. PUL21a-Cyclin A2 interaction is required to protect human cytomegalovirus-infected cells from the deleterious consequences of mitotic entry. PLoS Pathog. 2014;10:e1004514 pubmed publisher
	Pereira L, Petitt M, Fong A, Tsuge M, Tabata T, Fang Hoover J, et al. Intrauterine growth restriction caused by underlying congenital cytomegalovirus infection. J Infect Dis. 2014;209:1573-84 pubmed publisher

product information

Catalog Number :

MAB8121

Subcategory :

Infectious Diseases

Product Name :

Anti-Cytomegalovirus Antibody, blend, clone 8B1.2, 1G5.2, and 2D4.2

Product Type :

Antibodies

Clonality :

Monoclonal Antibody

Host Name :

Mouse

Antigen :

Cytomegalovirus

Clone :

8B1.2, 1G5.2, and 2D4.2

Conjugate :

Purified

Isotype :

IgG2a

Product Description :

Anti-Cytomegalovirus Antibody, blend, clone 8B1.2, 1G5.2, and 2D4.2

Cross Reactivity :

Human

ALT Names :

CMV

Immunogen :

MRC-5 infected cells with ATCC VR538 and AD169, ultrasonicated, screened by plate reduction neutralization tests.

Specificity :

Reacts with Immediate early, early, and late antigen preparations. Can detect CMV infection within 2 hours post-infection exhibiting a nuclear staining which reaches peak intensity between 48 and 96 hours. This antigen is persisting and can be detected during the complete CMV infection cycle. Staining of CMV structural antigens becomes apparent at about 48 hours. Extra-nuclear staining is first seen in the region of the golgi apparatus followed subsequently by staining of viral proteins and particles in the cytoplasm. With CMV the antigens expressed at different times are listed as: Immediate Early (alpha gene expression): those antigens expressed at 3-12 hrs post-infection generally involved in Transcription such as 72kD major phosphoprotein and a few other other antigens at 60 - 80kD. Early Antigen (beta genes) a.k.a. Delayed Early or Intermediate Early: expressed at 12-24hrs post-infection. Generally enzymes and one virion structural gene preceding viral DNA synthesis. Late Antigen (gamma genes): expressed at 36-48hrs post-infection. Generally structural proteins. Major protein = 55kD

Package Size :

100 µg

Uses :

Immunofluorescence;Immunohistochemistry

Storage :

Maintain at +2-8C in convenient aliquots for up to 6 months. Do not freeze.